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Zemuron Side Effects

Generic Name: rocuronium

Note: This page contains side effects data for the generic drug rocuronium. It is possible that some of the dosage forms included below may not apply to the brand name Zemuron.

It is possible that some side effects of Zemuron may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to rocuronium: intravenous solution

As well as its needed effects, rocuronium (the active ingredient contained in Zemuron) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking rocuronium, check with your doctor or nurse immediately:

  • Cough
  • difficulty with breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • noisy breathing
  • swelling at the injection site
  • tightness in the chest
Incidence not known
  • Difficulty with swallowing
  • hives, itching, or skin rash
  • muscular pain, tenderness, wasting, or weakness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to rocuronium: intravenous solution


Uncommon (0.1% to 1%): Arrhythmia, abnormal electrocardiogram, tachycardia
Rare (0.01% to 0.1%): Hypotension, hypertension
Very rare (less than 0.01%): Circulatory collapse and shock, flushing[Ref]


Rare (0.01% to 0.1%): Injection site edema, pruritus
Very rare (less than 0.01%): Angioneurotic edema, urticaria, rash, erythematous rash[Ref]


Uncommon (0.1% to 1%): Nausea, vomiting[Ref]


Very rare (less than 0.01%): Hypersensitivity, anaphylactic reaction, anaphylactoid reaction, anaphylactic shock, anaphylactoid shock[Ref]


Uncommon (0.1% to 1%): Asthma (bronchospasm, wheezing, or rhonchi), hiccup
Very rare (less than 0.01%): Bronchospasm
Postmarketing reports: Increased pulmonary vascular resistance[Ref]


Rare (less than 0.1%): Injection site pain, injection site reaction[Ref]


Rare (less than 0.1%): Prolonged neuromuscular block
Very rare (less than 0.01%): Muscular weakness
Frequency not reported: Residual paralysis, myopathy[Ref]

Nervous system

Very rare (less than 0.01%): Flaccid paralysis[Ref]


Uncommon (0.1% to 1%): Drug ineffective, drug effect/therapeutic response decreased, drug effect/therapeutic response increased
Frequency not reported: Malignant hyperthermia[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Zemuron (rocuronium)." Organon, West Orange, NJ.

3. Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL:" ([2006]):

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