Ticagrelor Side Effects

Some side effects of ticagrelor may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to ticagrelor: oral tablet

Along with its needed effects, ticagrelor may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ticagrelor:

More common
  • Difficult or labored breathing
  • shortness of breath
  • tightness in the chest
  • wheezing
Less common
  • Blurred vision
  • chest pain or discomfort
  • confusion
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • fast or irregular heartbeat
  • headache
  • lightheadedness, dizziness, or fainting
  • loss of consciousness
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • sweating
  • unusual tiredness or weakness
Incidence not known
  • Bleeding gums
  • bruising
  • coughing up blood
  • difficulty with breathing or swallowing
  • headache, sudden and severe
  • increased menstrual flow or vaginal bleeding
  • nausea or vomiting
  • nosebleeds
  • paralysis
  • prolonged bleeding from cuts
  • red or black, tarry stools
  • red or dark brown urine
  • weakness

Some side effects of ticagrelor may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Back pain
  • cough
  • diarrhea
Rare
  • Swelling of the breasts or breast soreness in both females and males

For Healthcare Professionals

Applies to ticagrelor: oral tablet

Hematologic

Hematologic side effects have included fatal/life-threatening bleeding such as intracranial; intrapericardial bleed with cardiac tamponade; hypovolemic shock or severe hypotension due to bleeding and requiring pressors or surgery; clinically overt or apparent bleeding associated with a decrease in hemoglobin (Hb) of more than 5 g/dL; transfusion of 4 or more units (whole blood or packed red blood cells (PRBCs)) for bleeding; major bleeding such as significantly disabling (e.g., intraocular with permanent vision loss); clinically overt or apparent bleeding associated with a decrease in Hb of 3 g/dL; transfusion of 2 to 3 units (whole blood or PRBCs) for bleeding; minor bleeding which requires medical intervention to stop or treat bleeding (e.g., epistaxis requiring visit to medical facility for packing); minimal bleeding such as bruising, bleeding gums, oozing from injection sites, not requiring intervention or treatment.

Cardiovascular

Cardiovascular side effects have included atrial fibrillation, hypertension, hypotension, chest pain, and bradycardia.

Musculoskeletal

Musculoskeletal side effects have included noncardiac chest pain and back pain.

Nervous system

Nervous system side effects have included headache and dizziness.

Respiratory

Respiratory side effects have included cough, dyspnea, exertional dyspnea, dyspnea at rest, nocturnal dyspnea, and paroxysmal nocturnal dyspnea.

Gastrointestinal

Gastrointestinal side effects have include nausea and diarrhea.

General

General side effects have included fatigue.

Endocrine

Endocrine side effects have included gynecomastia.

Hypersensitivity

Hypersensitivity side effects have included postmarketing reports of hypersensitivity reactions including angioedema.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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