Relistor Side Effects
Generic Name: methylnaltrexone
Note: This page contains side effects data for the generic drug methylnaltrexone. It is possible that some of the dosage forms included below may not apply to the brand name Relistor.
Common side effects of Relistor include: nausea, abdominal pain, and flatulence. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to methylnaltrexone: subcutaneous solution
As well as its needed effects, methylnaltrexone (the active ingredient contained in Relistor) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking methylnaltrexone, check with your doctor immediately:More common:
- increased sweating
- Bloody, black, or tarry stools
- severe abdominal or stomach pain, cramping, or burning
- trouble breathing
- vomiting of material that looks like coffee grounds, severe and continuing
If any of the following symptoms of overdose occur while taking methylnaltrexone, get emergency help immediately:Symptoms of overdose:
- cold sweats
- dizziness, faintness, or lightheadedness when getting up from lying or sitting position
Some methylnaltrexone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:More common:
- excess air or gas in the stomach or intestines
- full feeling
- passing gas
- stomach pain
For Healthcare Professionals
Applies to methylnaltrexone: subcutaneous kit, subcutaneous solution
Very common (10% or more): Abdominal pain (up to 29%), flatulence (up to 13%), nausea (up to 12%)
Common (1% to 10%): Diarrhea,
Postmarketing reports: Perforation, cramping, vomiting[Ref]
Common (1% to 10%): Dizziness, tremor[Ref]
Common (1% to 10%): Hyperhidrosis, flushing[Ref]
Common (1% to 10%): Chills
Postmarketing reports: Malaise, pain, cases of opioid withdrawal[Ref]
In an open-label, uncontrolled study (n=1034), 4 myocardial infarctions (1 fatal), 1 stroke (fatal), 1 fatal cardiac arrest, and 1 sudden death were reported. It is not possible to establish a relationship between these events and use of this drug.[Ref]
Frequency not reported: Myocardial infarctions[Ref]
The most common adverse reactions included abdominal pain, nausea, diarrhea, hyperhidrosis, hot flush, tremor, and chills.[Ref]
Common (1% to 10%): Injection site reactions including stinging, burning, pain, redness, and edema[Ref]
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Relistor (methylnaltrexone)." Wyeth Laboratories, Philadelphia, PA.
It is possible that some side effects of Relistor may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
More about Relistor (methylnaltrexone)
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.