User Reviews for Lubiprostone

Also known as: Amitiza

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Irritable Bowel Syndrome 22 reviews 125 medications
   
8.0
Constipation, Chronic 57 reviews 29 medications
   
7.3
Constipation, Drug Induced 0 reviews 2 medications Not rated - Be the first
Summary of Lubiprostone reviews 79 reviews 7.5

Reviews for Lubiprostone

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Review by LMSW (taken for 1 to 6 months): User Rating:  
   
9.0

Amitiza (lubiprostone) for Constipation, Chronic: I've had Irritable Bowel Syndrome and chronic constipation my entire life. Now at 23, after exhausting all over the counter and homeopathic remedies to no avail, I've decided to try a prescription. Overall, it works great and I don't plan to get off of it. What I have now is more like diarrhea than anything, but I'll take that over going up to 20 days without a bowel motion any day! I do get nausea about 30 minutes after I take it, and it gives me bad gas sometimes, but none of that is worth getting off of it. If you are seriously about to give up on life because of constipation, this medicine is for you! I recommend. I do also take Metamucil about every other morning, which helps the diarrhea. Also- the website for this product offers a $35 off prescription card.

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April 3, 2013 12:11 AM
Review by Bloatless (taken for 6 months to 1 year): User Rating:  
   
9.0

Amitiza (lubiprostone) for Irritable Bowel Syndrome: I developed Irritable Bowel Syndrome-C and chronic constipation after a C-section. I now take Amitiza 24mcg 2x per day. I've been on it for about 10 months. It works fantastic. I can "go" at least once a day now. Amitiza draws fluid from your body to increase bowel movement (I can actually hear it working) so it is important to drink a lot of water and eat before or immediately after. I've noticed that if I don't drink a lot of water, nausea will develop. In addition, IBS-C has caused me to change my diet and exercise. That helped a lot too. NOTE-- If the prescription costs a lot, even with insurance, Amitiza offers a discount card online.

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March 27, 2013 12:41 PM
Review by cbnsdn (taken for 1 to 6 months): User Rating:  
   
7.0

Amitiza (lubiprostone) for Constipation, Chronic: Amitiza works pretty good. I do still have to take Milk of Magnesia and mineral oil to feel completely emptied out. The severe nausea and headaches are very bothersome and sometimes they are worse than others. The side effects do go away once you have a bowel movement.

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March 23, 2013 10:17 AM
Review by rgraves550: User Rating:  
   
9.0

Amitiza (lubiprostone) for Constipation, Chronic: I take iron, Levothyroxine, I do not poo normally. I took some Amitiza and I remembered what normal felt like! Quality of life means everything. Pooping comfortably is a must for being happy!

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February 15, 2013 11:50 PM
Review by INmommX2 (taken for less than 1 month): User Rating:  
   
9.0

Amitiza (lubiprostone) for Irritable Bowel Syndrome: I have irritable bowel syndrome, Crohn's disease as well a Colon issues. My GI started me on Amitiza about 10 days ago. So far it has been great. I do have some cramping a little after a pill but not compared to the constipation cramping that I have had on & off for 15 years. I was lucky he gave me a sample pack good for a month so now I just have to hope my insurance picks it up next month.

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February 14, 2013 9:13 PM
Review by Quality of Life!: User Rating:  
   
10

Amitiza (lubiprostone) for Constipation, Chronic: 45 year old female with diagnosis of Chronic Constipation due to long term use of Med's, to include opioids for pain management. Also, diagnosed of Irritable bowel syndrome, around 8 years ago. When I'm taking this medicine, usually 2-3 times per day, I'm regular with a bowel movement of one to two times a day, depending on my diet and food intake (I eat very little on most days). Whenever I'm not taking this medication, I'm lucky if I'm able to go once over a 3-4 day time frame, even with laxatives, stool softeners, and my daily dose of lactulose syrup. I took Zelnorm about #8 years ago, until it went off the market, but Amitiza works much better, I asked my doctor to prescribe it after seeing a commercial for it, I've done well with it, only side-effect: flatulence.

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January 6, 2013 1:42 AM
Review by luisf: User Rating:  
   
6.0

Amitiza (lubiprostone) for Constipation, Chronic: Second day on this pill...severe diarrhea. I'm a dialysis patient so constipation is part of many pills. I think still afraid of going, outside thinking in use of restroom, dizziness, and weak. Good for emergencies but still thinking if someday I will be back to normality with no pills at all.

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December 26, 2012 3:11 PM
Review by sharut (taken for 2 to 5 years): User Rating:  
   
10

Amitiza (lubiprostone) for Constipation, Chronic: Actually - CIGNA covered this, but I now have United Health Care and they won't cover it unless you have irritable bowel syndrome or idiopathic constipation. I have constipation from M.S. and chronic opioid use and used it for over 4 years twice a day. I'm going to try lactulose but this pill is so much more convenient and for me, works without side-effects. Prior to this, only over-the-counter senna helped, but with cramping side-effects at times and only more than the recommended amount worked.

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December 3, 2012 3:34 PM
Review by tiffanyrogers1 (taken for less than 1 month): User Rating:  
   
9.0

Amitiza (lubiprostone) for Constipation, Chronic: I take the 24mg twice a day after having severe constipation post-chemo and multiple abdominal surgeries. It takes a couple of days for it to cause a movement, but when it does, it's unbelievable how much it works! I have felt the nausea and headaches, but didn't realize it was caused by the Amitiza. I'm so thankful to have this medicine!

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November 25, 2012 11:38 PM
Review by Anonymous (taken for less than 1 month): User Rating:  
   
1.0

Amitiza (lubiprostone) for Irritable Bowel Syndrome: This is my second attempt with Amitiza (this time at the lower dose). Unbearably nauseated once again on top of the constipation and abdominal cramping. Does not work for me AT ALL.

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November 9, 2012 3:19 PM
Review by Anonymous: User Rating:  
   
10

Amitiza (lubiprostone): I have only been takeing this for a week now but WOW. It works so good. It took 4 days to start it's action. It was like I was normal again. I am 31 and have had constipation my whole life. Higher fiber has got me through until a partial blockage and intestinal damage 2 months ago. Now with Amitiza I feel less bloated and a movement everyday on one pill in the morning. I feel so good! A little chest tightness but it gives me no nausea yet. This is a great medicine.

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October 14, 2012 10:43 PM
Review by Anonymous: User Rating:  
   
9.0

lubiprostone for Constipation, Chronic: Having two 8 mcg capsules daily and it does work with side effects. I have had some headaches and nausea. It helped my constipation a lot though. Bottom line it works for me.

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October 11, 2012 5:23 AM
Review by Anonymous: User Rating:  
   
5.0

Amitiza (lubiprostone) for Constipation, Chronic: I started taking Amitiza a month ago. I am on the 24 mg. It works sometimes but I am experiencing side effects that I didn't think resulted from this medication until I read some of the reviews. I have trouble taking in breaths, coughing, severe headaches, nausea, but most of all bloating and gas. Before the medication while being constipated, I could still button up my pants. Now that I've started the medicine, its a struggle due to bloating.

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September 20, 2012 4:29 AM
Review by Anonymous (taken for 6 months to 1 year): User Rating:  
   
5.0

Amitiza (lubiprostone) for Constipation, Chronic: I took this as directed for about 3 mos., and it was ineffective. I was still constipated. I stopped using it. Then I used it every 3 days when I needed to go, and it helped. Now I am taking it as directed and it seems to be working this time. So, inconsistent results. Stool is still hard and somewhat difficult to pass. Slight uncomfortable feeling when I am nearing having a bowel motion. Some nausea.

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September 19, 2012 11:10 AM
Review by Anonymous (taken for 1 to 6 months):

Amitiza (lubiprostone) for Irritable Bowel Syndrome: I love this medication. Nothing else has helped me with chronic constipation for my gastric paresis and irritable bowel.

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August 17, 2012 11:32 PM
Review by Anonymous (taken for less than 1 month): User Rating:  
   
1.0

Amitiza (lubiprostone) for Constipation, Chronic: Not so great for me. I have Crohn's disease with several (and I mean several) bowel resections for bowel obstructions. This medicine was given because I have had a full left gut on cat scan without a bowel obstruction. I now have severe and very weird (if you can believe weirder than my usual weirdness) bowel movements with some bad bum pain. Oh the joys of Crohn's!

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August 9, 2012 1:28 PM
Review by aerangel (taken for less than 1 month): User Rating:  
   
5.0

Amitiza (lubiprostone) for Constipation, Chronic: I have been on this for about a week. First few days, was amazed. Before this medicine I would do enemas every week or so due to pain, etc. The day after I took this medicine, I went three times, once after every meal. Wow! Same for the next few days. Side effects: Majorly tired, headaches that develop into migraine by end of day, weird feeling in chest and throat, breathing funny (like a bad cold) and VERY nauseated until I have a movement. Also, the last few days, only having movement every other day. So don't know what is going on. Need to try increasing the water and see how that goes. Don't know if normal bowel movements are worth all this, plus, it seems to not work as well as it did a few days ago.

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August 7, 2012 12:27 AM
Review by Cosmicblossom (taken for 1 to 6 months): User Rating:  
   
9.0

Amitiza (lubiprostone) for Constipation, Chronic: If you suffer with occasional constipation like me and you suffer from irritable bowel syndrome then this is a great medication. It is very safe with very little side effects that most women will already go through. Like headaches and random nausea and dizziness. I take this medication 2-3 pills twice a day and I feel so much better being on this medication. It isn't normal to go a day or two or three or even a week like what used to happen to me without having a bowel movement. This medication will help you release all that waste you need to. It works great for me. IBS is not a fun condition but I guess it's just for all of us lucky people to struggle with and experiment trial and error. Give Amitiza a try it really works. Good luck!

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August 3, 2012 12:10 AM
Review by kiki's mom (taken for less than 1 month): User Rating:  
   
10

Amitiza (lubiprostone) for Constipation, Chronic: For the first time in years my lower abdomen didn't feel full all the time.

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July 18, 2012 3:21 PM
Review by Anonymous (taken for less than 1 month): User Rating:  
   
10

Amitiza (lubiprostone) for Constipation, Chronic: It works perfectly. I have been battling with chronic constipation for far too long. No matter how much water, fiber or exercise I do nothing gets my bowels moving. Amitiza worked fantastic, I took three pills (one a day, as prescribed by my doctor) and went to the bathroom everyday for a week. Unfortunately, my doctor gave it to me as a test. My only complain is that Amitiza is far too expensive. Insurance does not cover it.

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June 27, 2012 8:39 PM
Review by BellyBloat (taken for less than 1 month):

Amitiza (lubiprostone) for Constipation, Chronic: I've have suffered from constipation for about 10 yrs now. I would use a laxative once or twice a week. Tired of laxatives so Doctor prescribed Amitiza. The first 2 days I suffered from severe nausea and had to lay in bed for an hour or so till it passed. Then I had extreme diarrhea that lasted the whole day. So far it seems that I'm only experiencing light nausea with the first dose, which seems to subside when I fill my stomach with food. It has been a full week now that I've been taking it and have yet to have a full bowel movement. I have constant gas and pains. I feel like I have to have a movement but when I go to the bathroom I find I still have to strain and nothing really comes out.

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June 7, 2012 8:16 AM
Review by SuIIyX (taken for 5 to 10 years): User Rating:  
   
8.0

Amitiza (lubiprostone) for Constipation, Chronic: I have been on Amitiza for five years, and am truly grateful for it. I was lucky to have a bowel movement every 5-7 days before Amitiza after trying other prescriptions, Miralax and high fiber diets, and this medicine was a God-send. When I was recently hospitalized for two weeks, the hospital did not carry the medication and I had to wait five days to have someone bring it from home and have it approved by the hospital pharmacy to give to me, and I paid the price for being off it for that long. I am astonished when doctors have not heard of this medication because it has been my savior from constant constipation.

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May 15, 2012 10:44 AM
Review by Anonymous: User Rating:  
   
8.0

Amitiza (lubiprostone) for Constipation, Chronic: I've had chronic constipation for 8 years now and I can go anywhere between one to three weeks without a movement. My doctor prescribed me Amitiza and I'm now having a movement every other day. The only reason I didn't give a ten is the side effects are brutal. I've eaten a full meal and drank water and I've still gotten terrible nausea and I've even vomited from it. And the headaches don't give a good impression either. But I would rather deal with that than the horrible constipation. Overall I love it!

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April 16, 2012 4:55 PM
Review by Anonymous: User Rating:  
   
1.0

Amitiza (lubiprostone) for Constipation, Chronic: After having chronic constipation for several years and having nothing but laxative, I was prescribed Amitiza. I have been on it for 3 weeks and can't take it. I have bloating so bad and am backed up that I must return to my laxatives. Back to the doctors for a specialist referral. Good luck to all others though.

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March 24, 2012 12:53 AM
Review by Empty in AL: User Rating:  
   
10

Amitiza (lubiprostone) for Constipation, Chronic: Have had problems for over 4 years. Nothing worked. Tried everything doctor said (gastro specialist), nothing worked. Finally a PA at a local clinic suggested Amitiza and what a change. No major side effects. Have even lost weight, more energy, no bloating and expecially no more digging the crap out just to get relief! No more bleeding and hemorroids from straining too much. Made me feel like a totally different woman. It also helped me control my blood sugar better. This is truly a miracle. Would not be without it.

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February 17, 2012 10:43 PM
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