Peripheral opioid receptor antagonists
A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Peripheral opioid receptor antagonists bind to the peripheral opioid receptors, such as those in the gastrointestinal tract and block unwanted effects caused by opioids.
They are not able to penetrate the blood brain barrier so do not antagonize central nervous system opioid receptors, therefore the analgesic effects of opioids is not affected.
Peripheral opioid receptor antagonists are given with opioids to prevent opioid-induced constipation.
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Medical conditions associated with peripheral opioid receptor antagonists: