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Penciclovir topical Side Effects

For the Consumer

Applies to penciclovir topical: topical cream

As well as its needed effects, penciclovir topical may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking penciclovir topical, check with your doctor or nurse as soon as possible:

Rare:
  • Mild pain, burning, or stinging

Severity: Minor

Some penciclovir topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Headache
Less common:
  • Change in sense of taste
  • decreased sensitivity of skin, particularly to touch
  • redness of the skin
  • skin rash

For Healthcare Professionals

Applies to penciclovir topical: topical cream

General

In clinical trials, 1 or more local side effects were reported by 3% of patients using penciclovir topical and 4% of patients using placebo.[Ref]

Local

Common (1% to 10%): Application site reaction (including skin burning sensation, skin pain, hypoesthesia)
Frequency not reported: Hypesthesia/local anesthesia, erythematous rash, taste perversion

Dermatologic

Frequency not reported: Mild erythema
Postmarketing reports: Allergic dermatitis (including rash, pruritus, blisters, edema), local edema, pain, paresthesia, pruritus, skin discoloration, urticaria, aggravated condition, decreased therapeutic response[Ref]

Nervous system

Postmarketing reports: Headache, parosmia[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity[Ref]

Other

Postmarketing reports: Oral/pharyngeal edema[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Denavir (penciclovir topical)." SmithKline Beecham, Philadelphia, PA.

It is possible that some side effects of penciclovir topical may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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