Nateglinide Side Effects
It is possible that some side effects of nateglinide may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to nateglinide: oral tablet
Along with its needed effects, nateglinide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking nateglinide:Less common
- Convulsions (seizures)
Check with your doctor as soon as possible if any of the following side effects occur while taking nateglinide:Less common
- Low blood sugar, including anxious feeling, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool pale skin, difficulty in thinking, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, or unusual tiredness or weakness
- Hives or welts
- redness of skin
- skin rash
Some side effects of nateglinide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- runny or stuffy nose
- sore throat
- Abdominal or stomach pain
- back pain
- pain in joints or muscles
- swelling in joints
For Healthcare Professionals
Applies to nateglinide: oral tablet
Nateglinide is generally well tolerated with the incidence of adverse effects similar to placebo. Upper respiratory tract infections, dizziness, flu symptoms, arthropathy, and accidental trauma were reported slightly more frequently than placebo in clinical trials.
Musculoskeletal side effects have included back pain (4.0%) and arthropathy (3.3%).
Respiratory side effects have included upper respiratory infection (10.5%), bronchitis (2.7%), and coughing (2.4%).
There were increases in mean uric acid levels for patients treated with nateglinide alone, nateglinide in combination with metformin, metformin alone, and glyburide alone. The respective differences from placebo were 0.29 mg/dL, 0.28 mg/dL, 0.28 mg/dL.
Endocrine side effects have included hypoglycemia (2.4%) and increases in uric acid.
Hypersensitivity side effects have included rare cases of rash, itching and urticaria in postmarketing experience.
Hepatic side effects have included post-marketing reports of jaundice, cholestatic hepatitis, and elevated liver enzymes.
More about nateglinide
- Other brands: Starlix
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