Nafarelin Side Effects

It is possible that some side effects of nafarelin may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to nafarelin: nasal spray

As well as its needed effects, nafarelin may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking nafarelin, check with your doctor immediately:

More commonFor adults (female)
  • Breast enlargement
  • light vaginal bleeding between regular menstrual periods called spotting
  • longer or heavier menstrual periods
  • vaginal bleeding between regular menstrual periods called breakthrough bleeding
For children (male)
  • Body odor
  • growth of pubic hair
For children (female)
  • Body odor
  • breast enlargement
  • growth of pubic hair
  • light vaginal bleeding between regular menstrual periods called spotting
  • longer or heavier menstrual periods
  • vaginal bleeding between regular menstrual periods called breakthrough bleeding
Less common
  • Chest pain
  • hives or welts
  • itching skin
  • redness of the skin
  • skin rash
  • shortness of breath
Less common or rareFor adults (female)
  • Fast or irregular heartbeat
  • numbness or tingling of the hands or feet
  • pain in the eyes or joints
  • patchy brown or dark brown discoloration of the skin
  • pelvic bloating or tenderness
  • unexpected or excess milk flow from breasts
  • unusual tiredness or weakness
For children (male and female)
  • Chest pain
  • hives
  • shortness of breath
Incidence not known
  • Anxiety or mental depression
  • changes in vision
  • chest pain or discomfort
  • cold, clammy, or pale skin
  • confusion
  • convulsions
  • headache
  • irregular heartbeats
  • nightmares or unusually vivid dreams
  • slow heart rate
  • vomiting
  • weakness
Incidence not known - For adults (female)
  • Cough
  • difficulty with speaking
  • dizziness or lightheadedness
  • double vision
  • fainting
  • fast heartbeat
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • nausea
  • pain or discomfort in the arms, jaw, back, or neck
  • pain, redness, or swelling in the arm or leg
  • slow speech
  • sudden shortness of breath or troubled breathing
  • sweating
  • vomiting
  • yellow eyes or skin

Some nafarelin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More commonFor adults (female)
  • Acne
  • dandruff
  • hot flashes
  • increase or decrease in sexual desire
  • increased hair growth, often abnormally distributed
  • mood swings
  • muscle pain
  • oily skin
  • pain during sexual intercourse
  • rapid weight gain
  • reduced breast size
  • stopping of menstrual periods
  • swelling of the feet or lower legs
  • vaginal dryness
For children (male)
  • Acne
  • dandruff
  • mood swings
  • oily skin
For children (female)
  • Acne
  • dandruff
  • hot flashes
  • mood swings
  • oily skin
Less common or rareFor adults (female)
  • Breast pain
  • headache (mild and transient)
  • irritated or runny nose
  • mental depression (mild and transient)
  • skin rash
For children (male)
  • Irritated or runny nose
For children (female)
  • Irritated or runny nose
  • white or brownish vaginal discharge

For Healthcare Professionals

Applies to nafarelin: nasal spray

Endocrine

Endocrine side effects have included hot flashes, decreased breast size, hirsutism, and decreased libido.

Genitourinary

Genitourinary side effects have included vaginal dryness.

Musculoskeletal

Musculoskeletal side effects have included myalgia and decrease in bone mass.

Psychiatric

Psychiatric side effects have included depression and emotional lability.

Respiratory

Respiratory side effects have included nasal irritation.

Dermatologic

Dermatologic side effects have included seborrhea and acne.

Hypersensitivity

Hypersensitivity side effects have included shortness of breath, chest pain, urticaria, rash, and pruritus in approximately 0.2% of patients.

Nervous system

Nervous system side effects have included headache and insomnia. Postmarketing reports have included convulsions.

Cardiovascular

Cardiovascular side effects have included edema.

General

General side effects have included weight gain or loss.

Hepatic

Hepatic side effects have included rare postmarketing reports of serious liver injury.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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