Nafarelin Side Effects
Some side effects of nafarelin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to nafarelin: nasal spray
Get emergency medical help if you have any of these signs of an allergic reaction while taking nafarelin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
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heavy or continued menstrual bleeding;
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pelvic pain or swelling;
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increased thirst, increased urination;
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seizure (convulsions);
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chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
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sudden numbness or weakness, sudden severe headache, confusion, problems with vision, speech, or balance; or
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nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects of nafarelin may include:
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changes in breast size;
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oily skin or acne, increased body odor;
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dandruff;
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increase in pubic hair growth;
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mood changes;
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runny nose;
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hot flashes;
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mild headache, muscle pain;
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light and occasional menstrual bleeding;
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white or brownish vaginal discharge;
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vaginal dryness; or
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changes in sexual desire.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to nafarelin: nasal spray
Endocrine
Endocrine side effects have included hot flashes, decreased breast size, hirsutism, and decreased libido.
Genitourinary
Genitourinary side effects have included vaginal dryness.
Musculoskeletal
Musculoskeletal side effects have included myalgia and decrease in bone mass.
Psychiatric
Psychiatric side effects have included depression and emotional lability.
Respiratory
Respiratory side effects have included nasal irritation.
Dermatologic
Dermatologic side effects have included seborrhea and acne.
Hypersensitivity
Hypersensitivity side effects have included shortness of breath, chest pain, urticaria, rash, and pruritus in approximately 0.2% of patients.
Nervous system
Nervous system side effects have included headache and insomnia. Postmarketing reports have included convulsions.
Cardiovascular
Cardiovascular side effects have included edema.
General
General side effects have included weight gain or loss.
Hepatic
Hepatic side effects have included rare postmarketing reports of serious liver injury.
More nafarelin resources
- nafarelin Nasal Advanced Consumer (Micromedex) - Includes Dosage Information
- nafarelin MedFacts Consumer Leaflet (Wolters Kluwer)
- Nafarelin Acetate Monograph (AHFS DI)
- Synarel Prescribing Information (FDA)
- Synarel Concise Consumer Information (Cerner Multum)
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