Nafarelin Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Endometriosis

200 micrograms intranasally daily. This is achieved by one spray (200 micrograms) into one nostril in the morning and one spray into the other nostril in the evening. Treatment should be started between days 2 and 4 of the menstrual cycle. In an occasional patient, the 400 microgram daily dose may not produce amenorrhea. For these patients with persistent regular menstruation after 2 months of treatment, the dose may be increased to 800 micrograms daily administered as one spray into each nostril in the morning (a total of two sprays) and again in the evening. The recommended duration of treatment is six months. Retreatment cannot be recommended since safety data for retreatment are not available.

Usual Pediatric Dose for Precocious Puberty

800 micrograms intranasally twice daily. This is achieved by two sprays (400 micrograms) into one nostril and two sprays into the other nostril twice a day.

If adequate suppression cannot be achieved, the dosage may be increased to 1800 micrograms intranasally per day administered as 3 sprays (total of 600 micrograms) into alternating nostrils three times a day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

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