Iodixanol Side Effects
Not all side effects for iodixanol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to iodixanol: injectable solution
Get emergency medical help if you have any of these signs of an allergic reaction while taking iodixanol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
urinating less than usual or not at all;
sudden numbness or weakness, especially on one side of the body;
sudden headache, confusion, problems with vision, speech, or balance;
feeling light-headed, fainting;
swelling in your hands, ankles, or feet;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
wheezing or trouble breathing; or
fever, chills, body aches, flu symptoms.
Other less serious side effects are more likely to occur, such as:
headache, dizziness, nervousness;
pain, warmth, or cold feeling where the medicine was injected;
numbness, warmth, or tingly feeling;
unusual or unpleasant taste in your mouth;
skin redness or itching; or
sleep problems (insomnia).
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
For Healthcare Professionals
Applies to iodixanol: injectable solution
Gastrointestinal side effects including nausea (2.8%), vomiting (0.8%), diarrhea (0.6%), and dyspepsia have been reported.
Other side effects including taste perversion (3.5%), parosmia (0.5%), and tinnitus have been reported.
Nervous system side effects including vertigo (2.4%), headache/migraine (2.5%), paresthesia (1.0%), agitation/anxiety/insomnia/nervousness (0.8%), sensory disturbance (0.8%), dizziness (0.7%), syncope (0.6%), cerebral vascular disorder, convulsions, hypoesthesia, stupor, amnesia, and confusion have been reported.
Cardiovascular side effects including angina pectoris/chest pain (2.2%), arrhythmias, cardiac failure, conduction abnormalities, hypotension, flushing, peripheral ischemia, cardiac arrest, hypertension, and myocardial infarction have been reported.
Dermatologic side effects including non-urticarial rash or erythema (2.1%), pruritus (1.6%), urticaria (0.5%), hematoma, and increased sweating have been reported.
Ocular side effects including scotoma (1.1%), cortical blindness, and abnormal vision have been reported.
General side effects including edema (0.6%), back pain, fatigue, and malaise have been reported.
Respiratory side effects including asthma, bronchitis, dyspnea, pulmonary edema, pulmonary embolism, respiratory depression, and rhinitis have been reported.
Hypersensitivity side effects including anaphylactoid reactions and pharyngeal edema have been reported.
Musculoskeletal side effects including polymyalgia rheumatica and dyskinesia have been reported.
Renal side effects including abnormal renal function, acute renal failure, and hematuria have been reported.
Metabolic side effects including hypoglycemia have been reported.
Hematologic side effects including hemorrhage have been reported.
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