Ibandronate Side Effects

Some side effects of ibandronate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to ibandronate: oral tablet

Other dosage forms:

Along with its needed effects, ibandronate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ibandronate:

More common
  • Bladder pain
  • bloody or cloudy urine
  • chest pain
  • cough producing mucus
  • difficult, burning, or painful urination
  • difficulty with breathing
  • fever or chills
  • frequent urge to urinate
  • lower back or side pain
  • nervousness
  • pounding in the ears
  • shortness of breath
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • tightness in the chest
Less common
  • Bloody or cloudy urine
  • body aches or pain
  • congestion
  • difficulty with swallowing
  • dizziness
  • dryness of the throat
  • fast heartbeat
  • frequent urge to urinate
  • hives
  • hoarseness
  • itching
  • numbness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • runny nose
  • skin rash
  • tender, swollen glands in the neck
  • tingling
  • unusual tiredness or weakness
  • voice changes
Incidence not known
  • Abdominal or stomach cramps
  • blurred vision or other change in vision
  • bone, joint, or muscle pain, severe and occasionally incapacitating
  • confusion
  • convulsions
  • eye redness
  • eye tenderness
  • heavy jaw feeling
  • irregular heartbeats
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loosening of a tooth
  • muscle cramps in the hands, arms, feet, legs, or face
  • noisy breathing
  • numbness and tingling around the mouth, fingertips, or feet
  • pain, swelling, or numbness in the mouth or jaw
  • sensitivity to light
  • severe eye pain
  • tearing
  • tremor
  • unusual pain in the thighs, groin, or hips

Get emergency help immediately if any of the following symptoms of overdose occur while taking ibandronate:

Symptoms of overdose
  • Acid or sour stomach
  • belching
  • bone pain
  • burning feeling in the chest or stomach
  • heartburn
  • indigestion
  • loss of appetite
  • pain or burning in the throat
  • sores or ulcers
  • stomach discomfort, upset, or pain
  • tenderness in the stomach area
  • vomiting
  • white spots on the lips or tongue or inside the mouth

Some side effects of ibandronate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Diarrhea
  • ear congestion
  • headache
  • loss of voice
  • pain in the extremity (arms and legs)
Less common
  • Cough
  • difficulty having a bowel movement (stool)
  • difficulty with moving
  • discouragement
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • general feeling of discomfort or illness
  • irritability
  • joint pain
  • lack or loss of strength
  • lightheadedness
  • loss of interest or pleasure
  • muscle aches and pain
  • muscle stiffness
  • pain, swelling, or redness in the joints
  • sensation of spinning
  • shivering
  • stuffy nose
  • sweating
  • tooth disorder
  • trouble concentrating
  • trouble sleeping

For Healthcare Professionals

Applies to ibandronate: intravenous kit, oral tablet

Gastrointestinal

Gastrointestinal side effects have included nausea, dyspepsia, diarrhea, tooth disorder, vomiting, gastritis, constipation and abdominal pain.

Metabolic

Metabolic side effects have included hypercholesterolemia. Hypocalcemia following dosing has been reported postmarketing.

Musculoskeletal

Musculoskeletal side effects have included myalgia, joint disorder, back pain, pain in extremities, localized osteoarthritis, muscle cramps and arthritis. Postmarketing side effects have included: severe or incapacitating bone, joint, or muscle pain; osteonecrosis of the jaw; and atypical, low-energy, or low-trauma fracture of the femoral shaft.

Cardiovascular

Cardiovascular side effects have included hypertension.

Nervous system

Nervous system side effects have included headache, dizziness, insomnia, vertigo, and nerve root lesion.

Respiratory

Respiratory side effects have included upper respiratory tract infection, bronchitis, pneumonia, and pharyngitis. Postmarketing side effects have included exacerbations of asthma.

Genitourinary

Genitourinary side effects have included urinary tract infection.

General

General side effects have included back pain, infection, asthenia, and influenza-like illness.

Dermatologic

Dermatologic side effects have included rash.

Hypersensitivity

Hypersensitivity side effects have included allergic reactions. Postmarketing side effects have included anaphylactic reaction/shock, and is some cases fatal, angioedema, bronchospasm, asthma exacerbations, and rash have been reported.

Ocular

Ocular side effects have included ocular inflammation such as uveitis and scleritis.

Renal

Acute renal failure has been reported postmarketing

Psychiatric

Psychiatric side effects have included insomnia and depression with intravenous ibandronate.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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