Albenza Side Effects

Generic Name: albendazole

Note: This page contains information about the side effects of albendazole. Some of the dosage forms included on this document may not apply to the brand name Albenza.

Not all side effects for Albenza may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to albendazole: oral tablet

In addition to its needed effects, some unwanted effects may be caused by albendazole (the active ingredient contained in Albenza). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking albendazole, check with your doctor or nurse as soon as possible:

Rare
  • Fever
  • skin rash or itching
  • sore throat
  • unusual tiredness and weakness

Some of the side effects that can occur with albendazole may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common
  • Abdominal pain
  • diarrhea
  • dizziness
  • headache
  • nausea
  • vomiting
Rare
  • Thinning or loss of hair

For Healthcare Professionals

Applies to albendazole: compounding powder, oral tablet

General

The side effects of albendazole (the active ingredient contained in Albenza) differ between hydatid disease and neurocysticercosis. The symptoms were generally mild and resolved without treatment. Treatment was discontinued primarily due to leukopenia (0.7%) or hepatic abnormalities (3.8% in hydatid disease).

Dermatologic

Dermatologic side effects have included reversible alopecia (1.6% in hydatid disease; less than 1% in neurocysticercosis). Erythema multiforme and Stevens-Johnson syndrome have been reported during postmarketing experience.[Ref]

Hypersensitivity

Hypersensitivity side effects have included hypersensitivity reactions (including rash and urticaria) in less than 1% of patients.[Ref]

Renal

Renal side effects have included acute renal failure during postmarketing experience.[Ref]

Hepatic

Hepatic side effects have included abnormal liver function tests (15.6% in hydatid disease; less than 1% in neurocysticercosis) and hepatotoxicity (greater than or equal to 1%). Hepatic abnormalities, acute liver failure, elevations of hepatic enzymes, and hepatitis have been reported during postmarketing experience.[Ref]

Hematologic

Hematologic side effects have rarely included granulocytopenia, agranulocytosis, pancytopenia, and thrombocytopenia. Leukopenia has been reported in less than 1% of patients. Aplastic anemia, bone marrow suppression, and neutropenia have been reported during postmarketing experience.[Ref]

Gastrointestinal

Gastrointestinal side effects have included abdominal pain (6% in hydatid disease), nausea/vomiting (3.7% in hydatid disease; 6.2% in neurocysticercosis).[Ref]

Nervous system

Nervous system side effects have included headache (1.3% in hydatid disease; 11% in neurocysticercosis), dizziness/vertigo (1.2% in hydatid disease; less than 1% in neurocysticercosis), raised intracranial pressure (1.5% in neurocysticercosis), meningeal signs (1% in neurocysticercosis).[Ref]

Other

Other side effects have included fever (1% in hydatid disease).[Ref]

Ocular

Ocular side effects have included retinal damage.[Ref]

References

1. "Product Information. Albenza (albendazole)." SmithKline Beecham, Philadelphia, PA.

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