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Albenza Dosage

Generic name: ALBENDAZOLE 200mg
Dosage form: tablet, film coated

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Dosage

Dosing of ALBENZA will vary depending upon the indication. ALBENZA tablets may be crushed or chewed and swallowed with a drink of water. ALBENZA chewable tablets are also available for children and patients who may experience swallowing difficulties. ALBENZA tablets and ALBENZA chewable tablets should be taken with food [see Clinical Pharmacology (12.3)].

Table 1: ALBENZA Dosage
 Indication  Patient Weight  Dose  Duration
 Hydatid Disease  60 kg or greater  400 mg twice daily, with meals  28-day cycle followed by a 14-day albendazole-free interval, for a total of 3 cycles
 Less than 60 kg  15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg)    
 Neurocysticercosis  60 kg or greater  400 mg twice daily, with meals  8 to 30 days
 Less than 60 kg  15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg)    

Concomitant Medication to Avoid Adverse Reactions

Patients being treated for neurocysticercosis should receive appropriate steroid and anticonvulsant therapy as required. Oral or intravenous corticosteroids should be considered to prevent cerebral hypertensive episodes during the first week of treatment [see Warnings and Precautions (5.3)].

Monitoring for Safety Before and During Treatment

  • Monitor blood counts at the beginning of each 28-day cycle of therapy, and every 2 weeks while on therapy with ALBENZA in all patients [see Warnings and Precautions (5.1)].
  • Monitor liver enzymes (transaminases) at the beginning of each 28-day cycle of therapy, and at least every 2 weeks during treatment with ALBENZA in all patients [see Warnings and Precautions (5.5)].
  • Obtain a pregnancy test in women of reproductive potential prior to therapy [see Warnings and Precautions (5.2)].
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