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Medications for Smoking Cessation

Discontinuation of the habit of smoking, the inhaling and exhaling of tobacco smoke.

Drugs used for Smoking Cessation

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
bupropion 8.0 325 reviews for bupropion to treat Smoking Cessation
Rx C N X
Generic name:
bupropion systemic
Drug class:
miscellaneous antidepressants, smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
varenicline 8.6 1643 reviews for varenicline to treat Smoking Cessation
Rx C N X
Generic name:
varenicline systemic
Drug class:
cholinergic agonists, smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
nicotine 7.8 193 reviews for nicotine to treat Smoking Cessation
Rx/OTC D N
Generic name:
nicotine systemic
Brand names:
Nicoderm CQ, Nicorette, Habitrol, Nicotrol Inhaler, Commit, Leader Nicotine Polacrilex, Nicotrol NS
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Nicoderm CQ 8.8 61 reviews for Nicoderm CQ to treat Smoking Cessation
Rx/OTC D N
Generic name:
nicotine systemic
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
Nicorette 6.2 39 reviews for Nicorette to treat Smoking Cessation
Rx/OTC D N
Generic name:
nicotine systemic
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Habitrol 6.4 8 reviews for Habitrol to treat Smoking Cessation
OTC D N
Generic name:
nicotine systemic
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
clonidine Off-label Rate Add review
Rx C N X
Generic name:
clonidine systemic
Drug class:
antiadrenergic agents, centrally acting
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
nortriptyline Off-label 9.4 7 reviews for nortriptyline to treat Smoking Cessation
Rx N N X
Generic name:
nortriptyline systemic
Drug class:
tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
topiramate Off-label 6.7 5 reviews for topiramate to treat Smoking Cessation
Rx D N X
Generic name:
topiramate systemic
Drug class:
carbonic anhydrase inhibitor anticonvulsants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
naltrexone Off-label 0.0 1 review for naltrexone to treat Smoking Cessation
Rx C N X
Generic name:
naltrexone systemic
Drug class:
antidotes, drugs used in alcohol dependence
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Nicotrol Inhaler 7.9 38 reviews for Nicotrol Inhaler to treat Smoking Cessation
Rx/OTC D N
Generic name:
nicotine systemic
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Commit 8.9 17 reviews for Commit to treat Smoking Cessation
Rx/OTC D N
Generic name:
nicotine systemic
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
Leader Nicotine Polacrilex 7.2 5 reviews for Leader Nicotine Polacrilex to treat Smoking Cessation
Rx/OTC D N
Generic name:
nicotine systemic
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
Nicotrol NS 6.5 6 reviews for Nicotrol NS to treat Smoking Cessation
Rx/OTC D N
Generic name:
nicotine systemic
Drug class:
smoking cessation agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

Frequently asked questions

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Alternative treatments for Smoking Cessation

The following products are considered to be alternative treatments or natural remedies for Smoking Cessation. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Smoking Cessation.

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.