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Tolnaftate

Pronunciation: tahl-NAFF-tate
Class: Antifungal agent

Trade Names

Aftate for Athlete's Foot
- Gel 1%
- Spray powder 1%
- Spray liquid 1%

Aftate for Jock Itch
- Gel 1%
- Spray powder 1%

Blis-To-Sol Liquid
- Liquid 1%

Genaspor
- Cream 1%

NP-27
- Liquid 1%

Quinsana Plus Foot Powder
- Powder 1%

Tinactin
- Cream 1%
- Solution 1%
- Powder 1%
- Spray powder 1%
- Spray liquid 1%

Tinactin for Jock Itch
- Cream 1%
- Spray powder 1%

Ting
- Cream 1%
- Spray liquid 1%

Pitrex (Canada)
Tinactin Plus (Canada)

Pharmacology

Distorts hyphae and inhibits mycelial growth in susceptible fungi.

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Indications and Usage

Treatment and prophylaxis of tinea pedia (athlete's foot); treatment of tinea cruris (jock itch) or tinea corporis (ringworm) caused by specific fungi; treatment of onychomycosis, chronic scalp infections, palm and sole infections with kerion formation; treatment of tinea versicolor.

Contraindications

Standard considerations.

Dosage and Administration

Adults and Children

Topical Apply small amount of ointment, cream, or powder or 1 to 3 gtt of solution to affected area twice daily for 2 to 3 wk (6 wk if skin is thickened); continue treatment to maintain remission. Reserve powder for mild infections.

Storage/Stability

Store at room temperature. Avoid moisture and sunlight. Keep powders from getting wet or damp.

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions

Dermatologic

Sensitization; mild irritation; pruritus; contact dermatitis; stinging.

Precautions

Pregnancy

Undetermined.

Lactation

Undetermined.

External use only

Avoid contact with eyes.

Nail and scalp infections

Do not use drug except as adjunct to systemic treatment.

Sensitization or irritation

Discontinue treatment if sensitization or irritation occurs.

Patient Information

  • Tell patient to cleanse skin with soap and water and dry thoroughly before applying.
  • Emphasize to use only externally in small amounts massaged well into affected area and surrounding skin.
  • Instruct patient to wash hands before and after applying medication.
  • Tell patient to avoid contact with eyes.
  • Advise patient to wear well-fitting, ventilated shoes and to change shoes and socks at least daily.
  • Tell patient not to cover treated site with bandages unless ordered specifically by health care provider.
  • Instruct patient to notify health care provider if there has been no apparent improvement after 10 days of treatment.
  • Emphasize that product should not be used on nail and scalp infections unless using in addition to internal medication prescribed by health care provider.
  • Tell patient to store at room temperature and not in bathroom (especially powders).
  • Instruct patient to report these symptoms to health care provider: persistent or severe irritation, itching, rash, stinging.

Copyright © 2009 Wolters Kluwer Health.

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