Skip to Content

Alogliptin / Metformin Dosage

Applies to the following strength(s): 12.5 mg-500 mg ; 12.5 mg-1000 mg

The information at is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Diabetes Type 2

12.5 mg alogliptin and 500 mg metformin or 12.5 mg alogliptin and 1000 mg metformin twice daily

Maximum dose: 25 mg alogliptin and 2000 mg metformin

Comments: Take with food. Do not split before swallowing

Renal Dose Adjustments


Liver Dose Adjustments

Not recommended


Consult WARNINGS section for dosing related precautions.


Alogliptin is minimally dialyzable and no dose adjustment guidelines have been reported; Metformin is dialyzable but no dose adjustment guidelines have been reported

Other Comments

Administration advice: Take with food. Do not split tablet prior to swallowing.

Patient advice: Acute or chronic excessive alcohol intake should be avoided. Hypoglycemia can occur when used with insulin or an insulin secretagogue.