Comparing Keytruda vs Methotrexate
Keytruda | Methotrexate |
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Keytruda (pembrolizumab) | Methotrexate |
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Prescription only
Keytruda is a type of immunotherapy that helps boost the immune system's response against cancer. It may be used to treat many different types of cancer in adults and children and is given by... View more |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Related suggestions Colorectal Cancer
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More about Keytruda (pembrolizumab) | More about Methotrexate | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Keytruda has an average rating of 4.3 out of 10 from a total of 214 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 58% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 330 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Keytruda side effects in more detail. |
See also: methotrexate side effects in more detail. |
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Generic Availability | |||||||||||||||||
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Keytruda prices |
View all methotrexate prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
N/A |
Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
624 hours |
15 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 16 drugs are known to interact with Keytruda:
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A total of 695 drugs are known to interact with methotrexate:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
N/A |
December 07, 1953 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.