Skip to main content

Esomeprazole for GERD User Reviews (Page 5)

Brand names: Nexium, Nexium 24HR, Nexium IV

Esomeprazole has an average rating of 5.6 out of 10 from a total of 179 reviews for the treatment of GERD. 46% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Esomeprazole

  • The...
  • Taken for 6 months to 1 year
  • March 30, 2021

Nexium (esomeprazole) "I took 20 mg for about a year. Heartburn was gone but at what cost? Painful joints and hips, fatigue. Feeling lousy. Lookup what the recent studies are saying about liver damage. This medicine starves your body of nutrients like calcium and magnesium which are highly essential. this can affect your bones). Also the low stomach acid creates a friendly environment for nasty bacteria that attack your organs. I have had my last dose of this very dangerous drug. Do your research and be aware."

1 / 10
Was this helpful?YesNo
5 Report
  • Schwe...
  • Taken for 6 months to 1 year
  • March 3, 2021

Nexium (esomeprazole) "I have had GERD since the 1990's. I have been on all different medication for this problem. No other pill has given me such problems like nexium. After using it for 2 weeks; got such achy bones all over that I was in constant pain. I have osteoarthritis but not all over as this. My stools are really soft and I go a lot. Sometimes 2x or 3x a day. If I pass gas sometimes I shart myself. I take nexium 3 to 4 times a week. My body can't handle 7 days a week. This by far has been the worst GERD medication that I have ever taken. It works for my GERD but the side effects are terrible."

3 / 10
Was this helpful?YesNo
5 Report
  • never...
  • Taken for 2 to 5 years
  • January 13, 2021

Nexium (esomeprazole) "I have been on Nexium for years. Have tried to get off it with no success. Last spring, summer, 2020 symptoms warranted a complete workup - lab , CT, upper endo - increased my nexium to 80 mg a day. I started (in hindsight) getting almost daily headaches, more depressed and irritable, then out of control anger. I though I was going crazy. I stopped Nexium 3 days ago. No more headaches, feel great, no irritability. I am now on 40 privacy? 2x a day . This is a horrible drug. Stay away at all costs. Plus , very expensive, - interesting in 3 x as much with insurance so I bought OTC. I think there needs to be atlas action suit against this drug - It is addictive and changes your body's ability to deal with reflux (proven in studies of people without GERD)"

1 / 10
Was this helpful?YesNo
5 Report

Frequently asked questions

  • Garde...
  • Taken for 1 to 2 years
  • September 13, 2022

Nexium (esomeprazole) "I've been on and off Nexium since the beginning of 2020. My GERD symptoms can get really bad if I don't follow a strict diet and a certain way to eat which is small portions and chew slowly. Sometimes I don't follow those rules, so I would need Nexium as soon as the GERD gets bad. Nexium does work for my worst symptoms, but I think this the last time I will take these tablets because it's definitely the reason why I was feeling so weird every time I took them. My side effects I would get are bloating, constipation, racing thoughts, mind pops and VERY creepy dreams and thoughts. I can't wait until the drug is completely out of my system. My tips for people struggling with GERD: - eat healthy - exercise - lower stress and anxiety - limit full cream, acidic food and spicy food - eat small meals - chew your food A LOT - don't drink liquids with food (this is my main cause of GERD) Avoid Nexium. It has so many lawsuits, yet it's still on shelves in stores."

2 / 10
Was this helpful?YesNo
3 Report
  • Kire
  • Taken for less than 1 month
  • March 11, 2020

"I started taking this drug for what I think is GERD, as I could not get a doctors appointment to get my prescription for omeprazole, after 3 days I decided never again would I take the drug . Terrible constipation, stomach pain, chest pain, head aches and feeling tired all the time. Morale of the story, wait to get an appointment..."

1 / 10
Was this helpful?YesNo
6 Report

Are you taking this medicine?

  • Anonymous
  • August 3, 2011

Nexium (esomeprazole) "It is the only medicine for reflux that works for me. Right now I am on a different medicine because my insurance won't pay for it and I even have trouble eating basic foods (with a good reflux medicine you should only have problems when you make a really wrong food choice; not normal food at normal times). The same insurance has paid for it for 3 years and now I since the end of June, I have been having to go through too much red tape to get Nexium, that works for me."

10 / 10
Was this helpful?YesNo
13 Report
  • Roe
  • Taken for less than 1 month
  • July 19, 2021

Nexium (esomeprazole) "I have really bad GERD been dealing with it for years, peptic ulcers, bleeding ulcer and hiatal hernia. I’ve tried my fair share of medications for this problem. I stopped using the meds a couple years ago and have been in agony with heartburn for a year now, I caved and got the nexium off brand at Costco. Literally less than a month in and my anxiety is INSANE. I’m so tired, jittery and anxious. I already have anxiety and depression so this just made it flare up and go nuts. I am stopping it tomorrow and going to speak to my dr about finding something that will work so I don’t live with the chronic heartburn but also so I don’t have to take stuff that gives me severe anxiety. This sucks!"

4 / 10
Was this helpful?YesNo
4 Report
  • Ellle
  • Taken for less than 1 month
  • August 29, 2021

Nexium (esomeprazole) "I only took it for 3 weeks and I had never been so sick in my entire life -Unable to eat without vomiting - Vomiting up acid for hours - Rash - Wheezing - Had to go to the ER twice and call an ambulance once - Couldn’t even drink water without vomiting - Panic attacks and suicidal thoughts This is pure awfulness"

1 / 10
Was this helpful?YesNo
4 Report
  • Joe...
  • Taken for 1 to 2 years
  • November 5, 2023

Nexium (esomeprazole) "I didn't sleep for about four months because I couldn't sleep due to acid reflux. After a bunch of tests, they figured out I had a hiatal hernia. I really had no choice because Tums doesn't work that well. I've been taking Nexium for a couple of years now, and honestly, I have very few symptoms. I haven't had any of the symptoms mentioned here."

10 / 10
Was this helpful?YesNo
1 Report
  • Mark...
  • Taken for 1 to 2 years
  • January 1, 2020

"I have taken generic nexium (esomeprazole) for a little over a year. I started by taking it every day. I experienced immediate relief which was a big surprise. I had heartburn for years and there were many foods I liked that I could not eat. Within 6 hours of taking my first pill I felt relief and it has not repeated itself unless I don't take it for 3 or more days. I am cutting back to 1 every other day and that should work well."

8 / 10
Was this helpful?YesNo
5 Report
  • Sick...
  • January 6, 2021

Nexium (esomeprazole) "I'm 60 years old 8 stone and really careful what I eat but for weeks on end I'll get GERD. It takes its toll and gets me down. I've tried lots of meds including nearly all the PPI's available. They all have side effects for me but Nexium was clearly the worst. It's a drug that actually worked well cured the GERD but I've given up with it as I get headaches, dry mouth, tinnitus twice as bad as normal and a fatigue like I have flu...the best of the worst for me is Rabeprazole. It's a debilitating illness that when you're doing nothing to aggrevate it , it flares up. I'd have an operation if there was one available but the doctors never give this as an option...just keep prescribing these strange drugs that make you feel dreadful"

5 / 10
Was this helpful?YesNo
4 Report
  • Dee
  • Taken for less than 1 month
  • February 17, 2022

Nexium (esomeprazole) "Was put on this medication for GERD, took it for 5 days. I do already battle anxiety and depression and since taking these meds my anxiety and depression has gone through the roof!!! Felt suicidal and am now booked into a Psych hospital. None of my doctors took me serious when I told them that that was the effects it had on me. Stopped taking it for 3 days and anxiety decreased. Was forced to take it again yesterday and I ended up not being able to sleep and woke up with anxiety again. I wish doctors would do more research on these meds and not just simply follow the leaflet on side effects."

1 / 10
Was this helpful?YesNo
3 Report
  • Wooww
  • September 21, 2021

Nexium (esomeprazole) "I'm so glad I found this! My fiance has had 2 severe panic. We couldn't figure out why. She literally thought she was dying and took her to the hospital twice. Thankfully before we would get there she would severely throw up and it would slowly go away. Today her grandma mentioned did this happen after taking the nexium and it did so I googled it and found this. It is so true. This medication is not safe. It could seriously hurt someone!"

1 / 10
Was this helpful?YesNo
3 Report
  • Fred...
  • Taken for 10 years or more
  • October 1, 2016

Nexium IV (esomeprazole) "SO....acid blockers pretty much changed my life. First was Pepcid (when it was prescription) than Zantac than the PPI's. The PPi's were a bit better. I got Acephix then Nexium. Before these wonder drugs came about I had CHRONIC gastro issues that eventually led to a week long stay at the hospital because of an ulcer. Anyway, been taking Nexium; works great. Prescription plan covered it than the patent runs out and they put it OTC. I get the generic & it's good but not as good. The OTC Nexium sucked! Now, Barock Insane O bOnghit stumbles in to the Whitehouse and screws up healthcare. Now generic Nexium is $175 because it's not covered under my prescription plan. Thanks, guys you really know ho to screw things up!"

8 / 10
Was this helpful?YesNo
6 Report
  • LOrina
  • January 28, 2010

Nexium (esomeprazole) "Excessive eating of chocolates and other sweets can lead me to have a sore throat. I asked my friend what to take and so she adviced me to take nexium. After a week of taking this medicine, my sore throat was gone. It was so amazing. I just love it!"

8 / 10
Was this helpful?YesNo
9 Report
  • MarcO
  • January 11, 2010

Nexium (esomeprazole) "I was ticked at first when TRICARE Prime refused to pay for the Nexium I had been prescribed when on Active Duty. Tried the VA too and they said no too. VA prescribed omeprazole and after two weeks of 40mg/day taken before two meals, I'm fine! No reflux. OK so far. Good because I like saving money."

9 / 10
Was this helpful?YesNo
8 Report
  • Gin
  • Taken for less than 1 month
  • September 28, 2021

Nexium (esomeprazole) "My cardoligist noticed that I had a cough and thought it might be acid reflux. I filled the script that day, (40 mg). The next day my gut was tender, I was light headed, had diarrhea. Three days in, the pain was worse, my migraines had become daily & acutely painful, nausea persisted, I was flatulent and even that caused severe gut pain. I felt nausea but thought it was a migraine related problem. I reasoned all my symptoms could not have been from 10 capsules that were supposed to help my cough. After I looked on line, I stopped the pills, thinking that would be the end of my pain but 6 days later I am still dealing with some side effects and the pain is just now easing up. Thanks to this site I finally put it all together. Never take ESOMEPRAZOLE, the generic for nexium. I have never had a side effect to anything, that was this painful, this hard to pin point, and took this long to clear up."

1 / 10
Was this helpful?YesNo
2 Report
  • Cat
  • Taken for 10 years or more
  • July 20, 2019

"I started taking Nexium (prescription 40 mg, 1X-daily) in my late 20's for recurring indigestion (Acid Reflux) after an endoscopy. I've been taking it every day now for 30-years.It has been a Godsend for me. I can't eat hardly anything with out it. Even though I've had endoscopies about every 5 years, I'm concerned, as in the past 4 years I've been diagnosed with seborrhea, rosacea, non-alcoholic fatty liver disease (NAFLD). I also have a horrible, chronic, nasty cough that I've had for as long as I can remember (no reason). Never smoked, don't drink & even though I rarely have an appetite, am overweight (was a size 4-6 my entire life until I became postmenopausal at 50). I also have some NEW tummy issues. I made an appointment with an endocrinologist TODAY."

7 / 10
Was this helpful?YesNo
3 Report
  • Etk
  • Taken for 1 to 6 months
  • November 5, 2020

"I had been on another PPI, my insurance would NOT cover it, so my gastro Dr changed me to Nexium. It worked ok from another pharmaceutical company. When I received my 90 day refill they changed pharmaceuticals to Camber. Unfortunately, things went south. Within a week of taken it, I noticed different changes, nausea, no appetite and sore throat. I continued taken for 3 weeks and then issues became really bad. I called my gastro and ENT Drs, got into see my ENT and I developed ulcerated laryngitis and ulcers through my esophagus and duodenum (confirmed by tests). Unable to take this Camber esomeprazole product, perhaps some quality control should be done."

1 / 10
Was this helpful?YesNo
2 Report
  • Beck
  • Taken for less than 1 month
  • August 20, 2019

"I thought nexium was my cure all. So to treat ulcers my doctor moved me to a prescription strength. One week after taking, I had severe abdominal pains, back and neck pain, headache, tender scalp and painful feet. Not to mention muscle spasms throughout my body. I just had my blood work done, and after this reaction, we did the blood work again. My c reactive protein was 31 (always under 1). Yikes! I described the pain in my stomach as a pain jumping from organ to organ like being kicked and stepped on and every now and then stabbed with a jolt of voltage. It scared the hell out of me. Even if you don't have a reaction, I wouldn't stay on this long."

1 / 10
Was this helpful?YesNo
2 Report
  • JoJo
  • November 24, 2021

"Was taking pantium up to a month ago and then switched to this drug...Have been feeling so nauseous the last 10 days and now I know why because it's all down to this tablet. Never again will I take this..My anxiety and stress levels are through the roof."

1 / 10
Was this helpful?YesNo
1 Report
  • Dude
  • Taken for less than 1 month
  • December 29, 2021

Nexium (esomeprazole) "Hi people I’m from England I thought I was loosing my mind but I having heath issues with this acid reflux belching all the time so I tried all given these medication. And I started to get upset all the time have bad nervousness. My stomach having issues, sleeping issues, bad shakes, headaches. I tried to talk to someone and all they do is look at you like you loosing your mind then on top of that had unexplained seizures now two year ago was the last time I had one and I was better. I thought great I can go for my car licence back but started to have issues again with belching. I was then given Nexium was on it for a day then back two seizures then rash on the side of my face then I passed out at work. Then did my blood pressure and that was so high that thought I was going to have heart attack so they kept me in over Xmas. I knew I was not loading my mind people be careful"

2 / 10
Was this helpful?YesNo
1 Report
  • Anonymous
  • Taken for less than 1 month
  • August 16, 2021

"Started this medicine for acid reflux. First few days were ok and it worked but then I started having bad side effects. Started getting violent episodes of hiccups that wouldn't go away until I vomited, always just felt full and needing to burp and just felt like my whole abdomen was wanting to spasm. After a few days, I started just feeling really anxious and panicky for no reason and I also had trouble getting to sleep. I also suffer from migraines and this medicine DEFINITELY made them worse and more frequent. I had no idea that heartburn medications could cause such terrible side effects. After a week I realized it was the nexium doing this and needless to say I have stopped taking it. After doing so, I felt like myself again after a few days."

2 / 10
Was this helpful?YesNo
1 Report
  • Homi...
  • Taken for less than 1 month
  • August 20, 2017

"Stress/anxiety ...GERD...always occurs. Worst is the revolting acid in nose and throat, waking in the middle of the night. For around 20 years. Other medication, ineffective...discovered, eventually, that certain foods, plus stress.. guaranteed GERD....One excellent treatment proved to be "Lait ribot"..always a bottle of it available. It's sour milk, like very thin yogurt. Eventually. ordinary milk, if drunk as soon as any symptoms occurred, stops a full on attack.. Best was to discover my own WORST gerd causing, foods, eg meat, bread, citrus fruits, cider, etc.. But medication essential for stressful business trips, with unidentifiable foods. Woke up at 2 am. Forgot the effect of cider! ..terrible acid. Just.One Pill! Gerd GONE!!!!"

8 / 10
Was this helpful?YesNo
2 Report
  • James
  • Taken for 1 to 6 months
  • September 16, 2021

"I have had a hiatus hernia for many years but it hasn't caused that many problems till about two years ago. The doc prescribed me everything under the sun inc Omi, Panto, Lanso and Esomeprazole. By far the worst of these was Esomeprazole, experienced all of the bad stuff which people have given reviews about. I stopped taking Esom for a while but the heartburn kept coming back so went back on it yesterday, big mistake! after two hours had delusions, lower right side back pain, bloating, shakes, headache, chest pain, diarrhea, dizziness, felt like a heart attack was going to happen (anxiety). Believe me when I say this medicine is an absolute nightmare! It may be alright for a few people to cure there acid reflux but you get a whole new set of problems with it which is far worse. A lot of people are on this for more than 14 days via docs prescriptions, that's like a death sentence! It is still being sold as a wonder drug online and in Chemists and supermarkets as well!! Steer clear!!!!"

1 / 10
Was this helpful?YesNo
1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.