Esomeprazole for GERD User Reviews (Page 4)
Brand names: Nexium, Nexium 24HR, Nexium IV
Esomeprazole has an average rating of 5.6 out of 10 from a total of 179 reviews for the treatment of GERD. 46% of reviewers reported a positive experience, while 40% reported a negative experience.
Reviews for Esomeprazole
- Lizzard...
- Taken for 10 years or more
- June 25, 2019
Nexium (esomeprazole) "I have been on nexium many years first 40mg and for a long time 20 mg . It controls the reflux but in spite of working on my diet if I go off of it for a few days I get very bad diarrhea and then might start to throw up stomach acid . Even tapering off might not work. I was originally diagnosed with a hiatial hernia. "
- Abba
- November 4, 2018
Nexium (esomeprazole) "I just want to say that if you have GERD and have a history of aspiration pneumonia, Do Not replace rxnexium 40MG with the OTC 24hr Nexium. They Are Not The same, after my mother wanted to try the otc Nexium for a few months, she developed Aspiration pneumonia after not having it for many years (10), she passed away"
Frequently asked questions
- molly
- Taken for 10 years or more
- January 24, 2020
"I have been taking the generic of nexium for about 10 years, every day, and have had no problems what so ever, but I take no other meds. I am 77 yrs old. Hope this helps others, if they are wondering if they can do this."
- RMM
- Taken for less than 1 month
- October 11, 2021
Nexium (esomeprazole) "Please be aware that this medication can cause anxiety, depression, and suicidal thoughts. Supposedly, it is a rare side effect, but I don’t have any allergies and I’ve never reacted to a medication like that before. When I was 19 years old (now 28) I had major stomach issues. I was diagnosed with gastritis and given this medication. I will never forget how it made me feel. I never want to feel like that again. I stayed up all night crying and staring out the window wishing I could just leave this world. I’m normally a very happy and content person. I will never ever take Nexium again. My doctor was able to give me another medication that made me better but I can’t remember what it was called. I only remember Nexium because of how horrible it was. The best way to describe it is Nexium made me feel like I was going crazy."
Are you taking this medicine?
- Anonymous
- November 30, 2009
Nexium (esomeprazole) "Took this a year ago for about 3 months, and seemed to work for the most part. Just had a little bit of stomach 'pain' due to the PPI's being blocked. Went off after that duration and had few issues. Later, I was on it for two weeks and it gave me strange side effects like lower abdominal aches in the back, a 'butterfly in the stomach' sensation that would not go away to the point where I would get 'attacks'. In the future, I'll only use this medicine for a week or so in case I really need it."
- Dusty
- Taken for less than 1 month
- March 22, 2018
Nexium (esomeprazole) "I took Nexium for three days (20 mg) and stopped due to explosive coughing which started day two. It intensified my asthma and caused diarrhea. I’m now five days out from stopping this drug, and I can’t get rid of these side effects. For me, this was a horrible drug."
- Anxie...
- Taken for less than 1 month
- November 12, 2021
Nexium (esomeprazole) "After having heartburn my doctor just automatically prescribed this to me. Let me tell you something! This is the worse thing I could’ve put in my mouth. My anxiety was off the roof! I ended up in the ER because I thought I was having a heart attack. I’ve always suffer from anxiety but this time it’s worse. Burning palm sensation, weird sensations in my brain along with pressure. My vision feels foggy and blurry, and I have arm and leg pain, and depersonalization. The list goes on. It’s been almost a month and I’m still suffering. I feel terrible. I wanted to quit my job and stay in bed! Although this may work for others. It can have bad effects on some. Use with caution!"
- Anonymous
- May 15, 2010
Nexium (esomeprazole) "I have taken NEXIUM for about 10 yrs. It works so good! Though the last 6 months I have used tums also. But the insurance says it isn't for acid reflux and won't let me have any more. Having a lot of trouble finding something that works! I want my Nexium back, it hurts so bad all of the time, even just a glass of water makes me hurt."
- Anonymous
- January 25, 2010
Nexium (esomeprazole) "I originally took this for three months a year ago. It worked great during the time with minimal side effects. Went off of it with no problem and had no heartburn for quite a long time. When I had an acid reflux episode last fall, I took it for about a week, where all these weird side effects happened. Developed lower right back pain, joints kept cracking when moving, and the occasional stomach pain in the lower left abdomen. Am disappointed since it was the only thing that really helped my reflux."
- Anonymous
- May 29, 2008
Nexium (esomeprazole) "I have very severe acid refulx with esophagal ulcers. I have tried tons of other medications and this is the only one that has given me relief without needing to supplement with antiacids! I do experience headaches as a side effect but they are mild and worth the relief."
- Bomber
- July 27, 2021
Nexium (esomeprazole) "I’ve been on over the counter nexium 20 mg for 6 daily doses as I hadn’t been able to pick up my omeprazole prescription. My god I thought I was dying! Massive panic attack yesterday nausea dizziness and early morning insomnia followed by crazy thoughts diarrhoea and eye twitches . I still have waves of nausea had no idea what it was until I visited these shared experiences I’m off it now and this review site has settled my nerves ! This stuff is utterly toxic ! Steer clear !Thank you all"
- nexium...
- February 2, 2009
Nexium (esomeprazole) "Nexium worked great for me too. After two years of use I developed high blood pressure. Maybe related to Nexium (known rare side effect) or maybe not. Stopping the drug seems not possible. Heartburn comes back, and it is very severe. "
- PSano
- March 24, 2018
Nexium (esomeprazole) "I started Proton Pump Inhibitors after cancer treatment in 1998. I started with a mild medicine and progressed as things got worse to Nexium twice a day. I haven't had the side affects others seem to have had so I guess I am lucky in that way. It has helped the acid reflux for sure. But one side effect I haven't seen here is ED. For Men taking this medication, if you begin to experience ED consult your doc and see if there is something else that could be used"
- mygerd
- December 17, 2011
Nexium (esomeprazole) "Over the years I have taken it "as needed". I try to control the acid reflux by watching what I eat. Mayo, Chocolate, mints, tomato sauces really set it off. Sometimes I forget. I try to take it as infrequently as possible because I have heard it may be responsible for decreasing bone density (I"m 69) and there may be other side effects. I was averaging one every 4-5 days. If I'm very careful can go longer, but sometimes I want to splurge. Today I refilled a prescription and noticed it was for "DR" delayed release. Anxious to see if there is any difference."
- Roonie
- March 30, 2021
Nexium (esomeprazole) "Doctor told me to take nexium for heartburn. Within a day made me feel bloated, head ache, tired, stomach cramps, serious constipation for 3 weeks and low mood, I took this for 3 weeks on and off. Had no idea it was nexium that was making me feel awful, thought it was my body which made me worry a lot. It worked well for heartburn but the side effects were awful. Would never take it again."
- Gina
- Taken for less than 1 month
- March 28, 2021
Nexium (esomeprazole) "That nexium needs to be off the shelf. That nexium 40 mg O took it for four days and gave terrible headaches and body feels sick. I will never take another PPI again. I started it four days ago today. Who made that awful drug."
- lplp
- May 27, 2020
"Its my 5th day using Nexium for my GERD. The effects were great in treating my heartburn but just this morning, my skin began to feel itchy, the muscles on my arms, legs and shoulder began to ache and weak. I just contact my doctor to confirm if it was good or not. I hope this could heal immediately."
- Anonymous
- November 9, 2020
"I was prescribed esomeprazole for acid reflux. I've taken 1 and my stomach feels as if its being pulled out. Burning and aching all night. Headache and just feeling really rough. Worst drug I've ever taken. Will never take it again I'd sooner have reflux than the pain and discomfort of that drug."
- Mike...
- Taken for 5 to 10 years
- November 16, 2018
Nexium (esomeprazole) "I thought the Nexium Clear Minis would be a good choice since they're so small they should be very easy to swallow. Today I think I aspirated the capsule as I took it early this morning and coughed it up finally this evening. In the windpipe it didn't dissolve like it would in the esophagus and stomach so it was partially intact. Scary and relieved that it didn't go further into my lungs!!!"
- Tjano
- Taken for less than 1 month
- October 7, 2019
Nexium (esomeprazole) "I had been taking Somac (brand of Pantoprazole) for a possible ulcer, then a pharmacist suggested Nexium. Within hours I had bad nausea. Next day I read it causes bad nausea, went back pharmacy, the chemist confirmed nausea and sweating. I had both -so no more for me"
- Mads4it
- Taken for 5 to 10 years
- August 8, 2023
Nexium (esomeprazole) "I have GERD intermittently, as a side effect of another illness. I only get symptoms when I lie down in bed or get ready. I only take it when I feel the symptoms escalating at bedtime, and if I take it on time, the symptoms subside rapidly and I can comfortably go to bed within a few minutes. I feel bad that the experience might be completely different for others. But I'm glad that for me, it works perfectly."
- mslad...
- January 10, 2009
Nexium (esomeprazole) "I have tried everything to ease the pain and discomfort of acid reflux. Then I was introduced to the "purple pill", Nexium, about three years ago and to my total surprise it worked. So now I'm a "firm believer" in the product. I'm very, very satisfied. Thank you Nexium!"
- Anonymous
- February 20, 2010
Nexium (esomeprazole) "I had excess acid all of my life including as a child. As an adult I was miserable because all of my friends and family could eat anything at any time. I often would sit up in bed for hours trying to sleep. I tried everything, then my doctor put me on Nexium. I has been heaven. I eat normally. I sleep normally. I don't hurt, belch, and/or throw up any more. No side effects after over two years. Love this stuff."
- Anonymous
- June 1, 2009
Nexium (esomeprazole) "After using Nexium for many years, I have abdominal pain and lots of wind and constant diarrhea. Loperamide did not control this. Now I am on a strict no carbohydrate, no dairy and no caffeine diet. It is working at this time, June 2009."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
Learn more about GERD
- Gastrointestinal Disorders
- Low Salicylate Diet
- Stomach / Heartburn Medications and Alcohol Interactions
Care guides
- Barrett Esophagus
- GERD (Gastroesophageal Reflux Disease)
- GERD (Gastroesophageal Reflux Disease) in Children
Symptoms and treatments
Medicine.com guides (external)
More about esomeprazole
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- Reviews (267)
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- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Drug class: proton pump inhibitors
- Breastfeeding
Patient resources
- Esomeprazole drug information
- Esomeprazole injection
- Esomeprazole (Intravenous) (Advanced Reading)
- Esomeprazole (Oral) (Advanced Reading)
- Esomeprazole strontium (Advanced Reading)
Other brands
Nexium, Nexium 24HR, Nexium IV
Professional resources
- Esomeprazole monograph
- Esomeprazole (FDA)
- Esomeprazole Capsules (FDA)
- Esomeprazole Injection (FDA)
- Esomeprazole Oral Suspension (FDA)
- Esomeprazole Strontium Capsules (FDA)
Nexium (esomeprazole) "I had two months of daily awful heartburn. I wasn't eating the best and I was drinking alcohol. Well, that part didn't stop, but I did take Nexium. It was amazing. During the 14 days I lightened my diet but still ate the things I enjoyed. I'm 35, and I think this is my first "medication" review, lol."