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Esomeprazole for GERD User Reviews (Page 3)

Brand names: Nexium, Nexium 24HR, Nexium IV

Esomeprazole has an average rating of 5.6 out of 10 from a total of 179 reviews for the treatment of GERD. 46% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Esomeprazole

  • Anonymous
  • Taken for 10 years or more
  • April 25, 2018

Nexium (esomeprazole) "I have been taking nexium for over 14 years now and can not speak highly enough of this drug. Before Nexium I was eating quikezze like they were lollies. Now one 20mg dose all this time daily with the only side effect being gas in the mornings. This has been a wonder drug for me"

10 / 10
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26 Report
  • Anonymous
  • Taken for less than 1 month
  • June 22, 2012

Nexium (esomeprazole) "I started with really bad nausea and sick to my stomach when I went to my GI doctor I was diagnosed with due densities and chronic gastritis. I was so sick with nausea twenty four seven I literally felt like I was going to die. I actually told my GI to prescribe me Nexium 40 mg. My GI was hesitant but I insisted took it for a about a month and half and on my second endoscopy my chronic gastritis had gone down to mild gastritis and the nausea is almost gone. Nexium really helped me I don't know about the side effects since I took it at night. But the nausea was still persistent it's just now going away. I can tell you this is one of the best medicines. Stops the acid production by 95 percent something I had to find out on my own. Good luck."

9 / 10
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43 Report
  • Bert
  • Taken for 5 to 10 years
  • January 8, 2020

Nexium (esomeprazole) "I started taking Nexium in my teens (20 years ago) for persistent acid reflux. At the time it relieved the nausea I was experiencing and I used it on and off for about 7 years before stopping completely. One thing I did suffer with during those 7 years was chronic diarrhoea, which at the time was diagnosed as IBS. After I stopped Nexium completely the pattern of chronic diarrhoea went away. That is until this past year when I was re-prescribed Nexium to deal with heartburn. When it works Nexium is great and I have no problem tolerating the side effects to gain what relief I can from reflux. However, I've noticed this time around it's working very slowly to alleviate my heartburn pain, if it alleviates it at all, and it's made dealing with any side effects increasingly frustrating."

5 / 10
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20 Report

Frequently asked questions

  • Eddie...
  • November 23, 2017

Nexium 24HR (esomeprazole) "had GERD for 3 weeks couldn't even sleep at night. So I decided to try nexium 24 hour after a bit of research. I've been on it now for 5 days and for me it works wonders. Now I can even eat , got my appetite back. All I can say after reading a lot of reviews pros and cons it really helped me but to each his or hers own. I had nothing to lose."

10 / 10
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27 Report
  • Anonymous
  • November 18, 2012

Nexium (esomeprazole) "I've had GERD since I was 14 and I had tried all sorts of OTC and prescription medicines. Most of them worked ok, but I would still have to pop a few Tums before I went to bed. After starting on Nexium I feel great! I've yet to have any signs of heartburn and I haven't had any side effects. This is the most expensive prescription I've had but the cost is well worth it."

10 / 10
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39 Report

Are you taking this medicine?

  • Batyah
  • Taken for less than 1 month
  • November 12, 2019

Nexium (esomeprazole) "After a couple of hours of taking Nexium I began to feel nauseous, another hour or so later I vomited. Then the diarrhea started. Watery and urgent I couldn't leave the house. I have tried this medicine several times and every time I have had the same reaction. It is the worst medicine I have ever been prescribed and I am going to destroy the ones I have left. The dosage I was prescribed was 40mg and this may well be too much but I will not try to take it again. "

1 / 10
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19 Report
  • Jamie
  • Taken for less than 1 month
  • September 29, 2021

Nexium (esomeprazole) "I couldn't figure out what was going on with me - I had extreme apathy (apathy is when you lack motivation to do anything or just don't care about what's going on around you)...which is very unlike my character. I was struggling with GERD, just short term for unknown reasons so I decided to try the 14 day Nexium course of treatment. I stopped at day 11. I could not stand the mental health effects it had on me. It brought back my anxiety and panic attacks full force. Why is this not discussed more often? No, none of you are crazy. We can't all have the same issues and be brushed off by the medical profession. I am a registered nurse and will never endorse this medication."

3 / 10
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  • Elena
  • March 6, 2010

Nexium (esomeprazole) "Diagnosed with acid hitting my throat (LPR). Have a small stomach hernia that is not allowing sphichter to close. It was a rough 6 month till I was diagnosed. 3 Doctors insisted I had allergies. Found another Doctor that finally that advised I had "silent acid reflux". Have cut out all the usual foods that cause more acid but in my case, my ears hurt (they tell me you have lots of nerves through the throat that go up to the ears and sinuses). Symptoms are: burning ears, flaring up through the sinuses, pain in the back of the neck up through the top of the back of my head. Have been on Nexium for 3 months. It helped but flaring returns 10-50%. Have come off Nexium to do the tests on how my GI is working. Nexium helped but lots of side effects."

6 / 10
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42 Report
  • Johnin...
  • Taken for 1 to 2 years
  • November 9, 2014

Nexium (esomeprazole) "I have been using Miralax and psyllium every night for about a year and wanted to try Linzess, but my doctor was hesitant to let me try it. Possible side effects. Anyway, after some research, I realized the Nexium I have been using causes a Magnesium deficiency. So now I take a multi-mineral capsule and a 500mg Magnesium capsule 3 times a day with meals. I have been able to cut back on my prescribed medications and have some hope that I will be able to get off them completely by adjusting my mineral intake. Try this, because your bowels cannot function without enough minerals."

4 / 10
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30 Report
  • Cherr...
  • Taken for less than 1 month
  • October 21, 2016

Nexium (esomeprazole) "I took Nexium for all of three days. In that time I found it to be extremely effective in managing my reflux/stomach symptoms. However, within a day I noticed severe anxiety surfacing. I take Aropax (paroxetine) for depression and this is not on the list of medications that is counterindicative. I do note that being magnesium deficient is but my doctor would not care enough to know that I have always had this deficiency. I do not normally suffer from headaches but began to have gentle pains in my head, getting worse over the time. The head pain and anxiety lasted as long as the effect on my stomach which was a number of days after I stopped taking the medication."

3 / 10
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25 Report
  • Riot
  • Taken for 5 to 10 years
  • May 8, 2018

Nexium 24HR (esomeprazole) "Asthma Physician prescribed Nexium 40mg for me after I needed to use my asthma inhaler 4 times a day. Over time, I was diagnosed with long standing Hiatal Hernia and GERD. I continue to use Nexium to manage my breakthrough Reflux and the result has been wonderful for me, save for occasional nuisance bloating. Thanks."

9 / 10
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20 Report
  • KPano
  • Taken for less than 1 month
  • October 12, 2019

Nexium (esomeprazole) "I was prescribed this for possible stomach ulcer and GERD. Within 30 minutes of taking this I had sharp chest pains when inhaling. The ER dr said it was a panic attack- it wasn’t, not my usual panic attack symptoms. My Dr told me I was her second patient to experience that with the drug. Never took it again. Was then prescribed Zantac with out issues, but it is being recalled now. Not sure what else to take besides Tums."

3 / 10
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16 Report
  • Gerdg...
  • Taken for less than 1 month
  • July 10, 2021

Nexium (esomeprazole) "I took this 20mg twice a day as recommended by my doctor) and within 4 days I had palpitations, insomnia, extreme anxiety, dizziness, nausea and pins and needles in my neck and legs. Worse was at night when trying to lie down when there would be pressure in my head and chest and violent dizziness and nausea. I had two weeks of only sleeping 2 hours a night and peaked with 2 successive nights of no sleep and a visit to Accident & Emergency. Suddenly realised it was the tablets and stopped the, effects slowly going and sleeping at last."

1 / 10
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  • Plant...
  • Taken for 1 to 2 years
  • June 14, 2020

"I have tried many different medications for persistent heartburn and GERD for the last 20 or so years. Started with Tagamet (cimetidine), which helped, but not consistently. Switched to Prilosec (omeprazole) 40mg/day about 10 years ago. Also inconsistent (and I follow an anti-GERD diet out of necessity, and still suffered from sometimes debilitating heartburn and related digestive issues. When Nexium finally went generic (it was just too expensive before) I switched to that, taking two 40mg capsules/day, and it changed my life. This is a very high dose but I was completely desperate for relief, which I got within days. I never get flareups since starting on it, so for me it’s a wonder drug. I’m also well aware of the controversy around PPI’s, but luckily I have not suffered any side effects and take B12 and iron supplements, in addition to a multivitamin daily. I hope to eventually come down to one capsule/day instead of two, but for now that’s what works best."

10 / 10
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14 Report
  • Anonymous
  • February 12, 2012

Nexium (esomeprazole) "I have had GERD since I was 19 years. For some reason I eat Ketchup with everything. I am 31 now. I've use Nexium in the past and my acid reflux always went away. Recently I've had upper back pains, cold chills, stomach and heart burns and the worse belly pain ever after I ate. The doctor sent me for a blood test which came back negative for any infections. I was placed on Nexium. Within 2 days I felt much better. I would recommend this for anyone. Wish I tried it before I did the ultrasound of my kidney, liver and gallbladder together with a chest x ray. I guess you got to pay a high price for a good product like Nexium. But I don't mind. I feel much better now."

10 / 10
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31 Report
  • Bbwasil
  • Taken for less than 1 month
  • December 24, 2016

Nexium (esomeprazole) "I have a severe acid reflux and my doctor recommended Nexium. I took it only 5 days and experienced no difference whatsoever. Absolutely no change. I still have severe acids and to be honest the drug seemed to make my symptoms worse. As well I am 100% sure it interacts with antidepressants and lowers their effectiveness! So if you are taking SSRI, please be aware!"

1 / 10
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21 Report
  • Leeanne
  • November 11, 2020

Nexium (esomeprazole) "Beware of their marketing scam. I called the phone number on their marketing add on tv. I asked for a trial and the person said I would be charged a shipping fee of $7.95 . I said that was fine . They charged me $7.95 on Oct. 4th. On Oct 21st. I was charged $119.90. I did not receive the product until Oct. 30th. I called nexium and complained about the charge. They said, “I needed to call 14 days after trying the product to cancel the agreement”, I was not aware of any agreement because I only asked for a trial, and besides, I received the product 9 days after I was charged $119.90. How was it possible for me to try the product in 14 days to cancel the agreement that was not explained to me. They charged me even before I was able to try the product. Nexium did not work. I took it for 3 nights and stayed up all 3 nights! This is really a scam and I am disputing it."

1 / 10
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12 Report
  • Ashle...
  • July 28, 2015

Nexium (esomeprazole) "I have now been using Nexium 24 for only 4 days but I am seeing the effects already! I have been able to enjoy many foods I have had to avoid in the past with little to no burn. I absolutely have hope that Nexium is the answer to all my problems and that in time it will eliminate the problems all together. I was lucky enough to receive my Nexium free from a mission and now I'm a dedicated customer. Thank you so much for this awesome product!"

10 / 10
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24 Report
  • Xerk
  • Taken for 6 months to 1 year
  • December 22, 2019

"This medicine is toxic. After weeks of stopping my medication, I now have. 1. Muscle twitching 2. Nerve problems 3. Back, legs, shoulder pains (although my leg and shoulder pain have decreased) 4. Weight loss (I managed to recover my lost weight). 5. Vision problems (Although I think it has something to do with a wrong prescription glasses) 6. Anxiety / Panic Attacks I do not recommend taking this drug. If you want to reduce your stomach acid, I recommend Gaviscon and other antacids. NEVER USE PPIs."

1 / 10
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14 Report
  • Anonymous
  • June 18, 2009

Nexium (esomeprazole) "Nexium seemed to be the answer for the first 3 years but lately it has fallen short and all the pain has returned with vengeance. There always was the side effects of headaches, gas and elevated blood pressure."

4 / 10
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35 Report
  • Anonymous
  • September 2, 2009

Nexium (esomeprazole) "I thought it was working until I developed severe stomach cramps that wouldn't go away. Got scoped and discovered I had fairly severe damage to the esophagus which had reduced the efficiency of swallowing down to 10%. Don't assume the medication is working unless you get checked. They switched me to omeprazole. "

1 / 10
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34 Report
  • LPRguy
  • Taken for less than 1 month
  • March 7, 2022

Nexium (esomeprazole) "I was diagnosed with Laryngopharyngeal reflux (LPR) in 2018, in my mid-40s. This surprised me because I had zero problems with reflux in my life, and in fact never experienced heartburn ever. The doctor advised I take Nexium for my LPR, as well as abruptly cut out caffeine. The result was disastrous. I abruptly developed a crippling anxiety, depression, and anhedonia (lack ability to feel pleasure) problem, about a week later. I never had any of these conditions prior to taking Nexium and cutting out the caffeine! After about a few weeks, I tried quitting first the Nexium and then later bringing back the caffeine. A few days after doing both, my psychological condition rapidly improved. However, at the time I attributed my issues being from caffeine withdrawal, and not the Nexium. Wrong! I ended up being given Nexium again for something different, and the anxiety started to return! I quickly quit it, and went back to normal. If it makes you feel anxious, quit it now!"

1 / 10
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8 Report
  • Esome...
  • Taken for less than 1 month
  • June 28, 2022

Nexium (esomeprazole) "Omg I an so glad I found this website!! I took nexium 20mg 24hr for 2 weeks then my GI put me on 40mg and after taking it for 1 week I thought I was going crazy with all these horrible side effects such as anxiety, muscle twitches, bloating, belching, insomnia, heart palpation and much more!! Ended up in the ER, did an ultrasound and bloodwork and nothing came up so they must thought I was faking it. It raises my blood pressure, makes me so fatigue that some days I couldn’t even get out of bed. My mouth and eyes were so dry, brain fog and confusion…. Just HORRIBLE!! I’m so glad I went on here and found all these reviews, I will stop taking it!"

1 / 10
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7 Report
  • Paul...
  • March 8, 2015

Nexium (esomeprazole) "I suffered severe pain from GERD that I had to be hospitalized. The next day I bought the Nexium 24hr, not because I saw it was the top selling brand at Walmart, but because my mom said to get Prilosec lol. Anyway, within minutes the pain from my GERD disappeared. One con I've had so far though. The medicine states 24hrs, for me it's roughly 18-20 hrs and I start feeling the acid again. So keep that in mind."

10 / 10
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23 Report
  • Bry
  • Taken for less than 1 month
  • August 24, 2019

Nexium (esomeprazole) "I had two months of daily awful heartburn. I wasn't eating the best and I was drinking alcohol. Well, that part didn't stop, but I did take Nexium. It was amazing. During the 14 days I lightened my diet but still ate the things I enjoyed. I'm 35, and I think this is my first "medication" review, lol."

10 / 10
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14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.