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Asenapine for Post Traumatic Stress Disorder User Reviews

Brand names: Saphris, Secuado

Asenapine has an average rating of 8.6 out of 10 from a total of 17 reviews for the off-label treatment of Post Traumatic Stress Disorder. 88% of reviewers reported a positive experience, while 6% reported a negative experience.

Asenapine rating summary

8.6/10 average rating

17 ratings from 20 user reviews.

Compare all 16 medications used in the treatment of Post Traumatic Stress Disorder.

10
47%
9
18%
8
24%
7
0%
6
6%
5
0%
4
0%
3
0%
2
0%
1
6%

Reviews for Asenapine

  • Anonymous
  • Taken for less than 1 month
  • October 28, 2013

Saphris (asenapine) "I waited 3 weeks to write a review cause I was sceptical. After trying so many antidepressant and having the the reversed effect this is the one. I suffer from sever anxiety and PTSD. I take 5mg at night cause it does hit you like a rock. I tried the recommended dose 10mg after a week and it was too much. The taste is annoying but I will deal with that. I am able to concentrate and get things done. I exercise 5xs a week so I have not gained weight. My eating habits are fair so it's diffinatly the exercise. I been trying to find the right drug for 4 years and nothing helped. I do also take klonopin but since I have started saphris it's been reduced it to half of what I used to take. This med has helped me with my anticipatory anxiety"

9 / 10
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52 Report
  • jozey
  • November 22, 2013

Saphris (asenapine) "I have been on medication for over 23 years and Saphris is a far better antipsychotic I have ever been prescribed. I feel more motivated, more social, my weight hasn't changed and am now enjoying life unlike the many years I spent on Largactil and other antipsychotics. I have also felt benefits in my sleeping pattern. Use this medicine right and you wont believe the change. I have Borderline Personality Disorder and Post Traumatic Stress Disorder but also use an antidepressant too."

10 / 10
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50 Report
  • Kris...
  • Taken for less than 1 month
  • November 30, 2014

Saphris (asenapine) "I'm sleeping for the 1st time in YEARS without the screaming-clawing-gasping-horrors (the thing people refer to as "nightmares"). Waking up was the worst part. Waking up found me in a dead panic, or a blood-red rage, unable to function. Nothing helped, some things made me worse. I have been labeled "medication resistant" because nothing helped & I'd given up. No med-of-the-month for me. I've been suicidal for awhile, but hadn't told anyone. Had a breakdown while with Mom. I called my shrink, put her on speakerphone, & she called in a prescription for Saphris. I stayed with Mom. We got the medicine. Starting calming with the 1st dose. I now remember what sleep & rest feel like! Cleared my head. I still have my artistic creativity, too! "

10 / 10
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45 Report
  • Anonymous
  • April 24, 2012

Saphris (asenapine) "I have had depression and anxiety panic disorder, suicidal thoughts and post traumatic stress disorder for about 25 years. I've tried pretty much every medicine you can think of for these conditions. When I started on Saphris I started feeling better after the fourth day. I actually felt a little manic because I was cleaning my house like a normal person. I thought this could be it. Finally. It has been a miracle for me, I have nothing negative to say about this medicine it's wonderful. "

9 / 10
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53 Report
  • Grann...
  • Taken for 1 to 6 months
  • March 10, 2013

Saphris (asenapine) "I have been on Saphris for about 5 weeks. I started at a low dose, 5mg at bedtime and just increased to 10mg a couple days ago. I love this medicine! I sleep at night and wake up feeling good in the morning, I haven't experienced that in YEARS! My PTSD episodes have greatly decreased in intensity, duration and how often they occur. I really do feel like a new woman!"

10 / 10
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47 Report

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  • PTSDa...
  • Taken for less than 1 month
  • December 13, 2014

Saphris (asenapine) "I have Complex Post Traumatic Stress Disorder. Currently taking Effexor, Lorazepam, Remeron, Prazosin, Propranolol, and Saphris. Despite the medication regiment, I was having a very hard time with anxiety. The panic attacks were debilitating so my psych doc decided to try me on Saphris. He told me to take 5mg at night and 2.5-5mg in the morning if I needed it. The most noticeable side effects I've had are sleepiness, numb/tingly tongue, and clumsiness. The first three days, the taste of the tablet (regular "flavor") was awful. Today, about one week since starting, it's tolerable. My anxiety has reduced significantly. My flashbacks have reduced in severity, I feel more mellow and calm. Saphris is really helping me get the most out of my therapy."

8 / 10
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34 Report
  • heids
  • December 18, 2013

Saphris (asenapine) "I had very sudden onset post traumatic stress disorder, obsessive compulsive disorder and psychotic depression. What absolute hell I was going through for a good 18 months of doctors experimenting with different medicines on me. All the other antipsychotics had bad effects on me and made my depression worse. My last admission to hospital was for my own safety and as a last ditch effort when I was suicidal my psychiatrist thought we'd try Saphris. Within 4 days I noticed a complete change for the better. It helps me sleep but I suspect it also takes away a bit of my drive to exercise which I hate because I used to work in the fitness industry. I do take 2 other medicines so it could be the combination. Generally a positive experience with this medication."

8 / 10
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33 Report
  • Anonymous
  • October 17, 2012

Saphris (asenapine) "I have post traumatic stress disorder, anxiety disorder, and depression. My doctor started me on Saphris almost a week ago and as of this time I'm getting more sleep than I have in years! I'm very happy with the performance of this medicine."

8 / 10
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32 Report
  • Peach...
  • October 23, 2013

Saphris (asenapine) "I have been on this medication for 4 days now & I can't believe how at peace I finally feel after years of trying every pill combination possible by my dr to get me well. My racing thoughts are gone. My OCD is under control. I noticed even with little OCD problems I have it's as if my mind says "enough" & I'm satisfied. I'm was never satisfied before & in just 4 days these are my results. I also suffer from extrem anxiety and ADD I'm taking intuniv in the am & it's a great combanation off me. Is this too good to be true??!!"

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26 Report
  • Survi...
  • Taken for 6 months to 1 year
  • March 6, 2024

"I use 2.5 mg of orally disintegrating asenapine to treat PTSD, and specifically to treat near-constant auditory hallucinations or auditory flashbacks where I hear my captors questioning or threatening me. I take it at night because it usually makes me sleepy within about an hour. This medicine has saved my life."

10 / 10
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1 Report
  • Susie...
  • Taken for 1 to 6 months
  • May 1, 2017

"I have had severe insomnia since my mom died in 2011. Sometimes I would be awake and watching Netflix for days. I was too sluggish to go out or even do work in my home. I couldn't take one more sleepless night, and then my doctor gave me samples of Saphris. After the first pill and first night of sleep (falling asleep in about 10 minutes), I drove back and demanded a prescription and more samples. Its a VERY expensive medicine. However, my doctor had a coupon that offers 5 months for free ($13500/month value) and that's 60 count 10mg tablets, and I only need one for sleep, so this is a great deal! It has helped my mood as well, but having no insomnia saved my job. I give this medicine 10/10!"

10 / 10
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15 Report
  • Anonymous
  • September 7, 2011

Saphris (asenapine) "Feeling so much better since I started it. But, I do get the urge to eat within a half hour of taking. Also, I have pretty severe hyperprolactenemia. My breasts are swollen and painful. Had to buy a super large bra."

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22 Report
  • Mirro...
  • March 13, 2010

Saphris (asenapine) "Can't give a real good rate for this drug since I'm only taking it for the 2nd time today. It tastes bad, tongue numb for a few minutes after taking it. So far it is just making me tired and loopy and having some gas tonight. But then I have been very very tired for many months now and perhaps the extra sleep this allows will help me get back to normal again. I have had noises, shadows, and racing thoughts and flash backs to deal with that may have been due to anxiety etc.. Hope I don't have stomach upset in future as someone else mentioned that happening to them. I will have to return and give a new rating after I've been on this a while longer."

6 / 10
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14 Report
  • Simack
  • Taken for 6 months to 1 year
  • December 13, 2015

"Was great at first, but then noticed I slowly started developing anhedonia, severe memory and higher cognitive function issues. The real nightmare was trying to discontinue this drug. It's literally worse than hell, the anxiety is extreme, you're in a constant state of intense panic, it feels like your going to die. Then the intractable insomnia hits you, seriously don't take this drug or any other neuroleptic's for that matter."

1 / 10
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9 Report
  • Friend...
  • January 6, 2016

"I use Saphris PRN in conjunction with Xanax QID for anxiety. Takes the edge off at 5mg, makes me very sleepy, doesn't dampen Anxiety related tremor or stutter. Tastes yuck, but great for sleeping, 15 minutes and I'm down for 8 hours. My first experience with anti-psychotics off label use."

8 / 10
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7 Report
  • jmpat...
  • Taken for less than 1 month
  • November 3, 2015

"I have only taken one dose, but already feel more energy and a slightly better mood. I am taking this for depression. I also have anxiety, insomnia, and PTSD. I am also on Effexor 300mg, Propranolol 30mg, Clonazepam 1.5mg and Lamictal 200mg. After reading other reviews, I am hoping to get off some of these or at least decrease the dosage. I have not slept well in over 9 years, waking up every few minutes all night long. Last night, I only woke up 2x to go to the bathroom. Huge improvement. I took the medicine at 7:30pm, but I was awake by 5:45am and no groggy feeling. I am used to drinking espresso shots all morning to stay awake, but only drank 1 espresso today. I will update more as I go with this med. No side effects yet."

10 / 10
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7 Report
  • Anonymous
  • July 29, 2015

"Saphris has helped me a ton. My anxiety and insomnia were so bad that no other med would calm me down enough so that I could sleep. Saphris is very strange to me because unlike other drugs (seroquel, xanax) I do not feel it "kick in". All I know is that I end up asleep with no problems. If I am having a panic attack, I will take a dose of it and my symptoms completely go away within a half hour. It has been three years and it still works great."

10 / 10
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7 Report
  • KarlJS
  • July 28, 2015

"I've long suffered from insomnia. Ambien, Lunesta, and the new Belsomra were all total failures. I don't care for the weight gain risk of Seroquel, nor how it would simply replace insomnia with hypersomnia, causing me to sleep for 15 hours. That's not to mention the risk of diabetes, which I'm already at risk for due to obesity. I've tried TCAs (at max dose), antihistamines (at max dose & beyond), Remeron, Rozerem (and probably others I'm forgetting) and none helped with my sleep. Now some might take a benzo as a sleep aid, though being a guy who took Xanax at 10 mg per day for almost a decade, it seems exceedingly unlikely that any benzo is going to make me sleep. (Yes, TEN, lest you think I forgot a decimal point). Saphris works."

9 / 10
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5 Report
  • Jenna...
  • February 19, 2016

"One day and I feel amazing"

10 / 10
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8 Report
  • Bambina
  • Taken for less than 1 month
  • August 28, 2015

"Not sure yet"

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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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