The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Reviews for Amitriptyline to treat Migraine Prevention
Review by Migraine82:
amitriptyline: Works great to control my migraines it cut the frequency in half. Before starting this medication I would suffer migraines 3-4x/week. And the days that I didn't have a migraine, I still felt "foggy". However after only 6 weeks on it I gained 30 lbs, had urinary retention.
amitriptyline: After I had kids I started getting migraines. I've had them for over 5 yrs. I started taking this medication and I've been on them for a little over a month. The first few days (2 or 3) I slept like a rock. I even felt weird like I was in a dream. Those side effects went away after the third day. I haven't had 1 migraine since I started taking this medication, and I'm able to sleep through the night too. I would recommend this to anyone with migraines.
Review by Bugsybooboo (taken for 6 months to 1 year):
amitriptyline: After 20 years of migraine suffering I went private and was prescribed Amitriptyline 10mg. I took these for 5 months and barely had a headache never mind migraine. I got dry mouth and my sleeping improved also. However after 5 months the migraines have started to come back so I increased the dosage to 20-25mg, again the first few weeks I noticed the dry mouth and disturbed sleeping but this has not settled down again and migraine free. It's the best medicine I've ever had and had also helped with my neck and arm pain. I couldn't recommend it enough, a lifesaver.
10 users found this comment helpful.
amitriptyline: I have taken this medication for six years and it has really helped with my migraines and my inability to sleep or stay asleep. I started off at 10mg and slowly increased to 50mg and have been on the same dosage for the past four. The only downside is my absolute need to take it at the same time every night in order for it to make me sleepy otherwise I can stay up the entire night if I take it later than 9pm.
amitriptyline: I had 3 to 4 migraines a week and was sleeping very badly.
2 weeks into taking amitriptylne and the migraine gone.
I'm sleeping at least 7 hours a night too.
I don't know if this will last, but it's working brilliantly at the moment. The initial tiredness side effect stopped 1 week in.
18 users found this comment helpful.
Review by GiselleL (taken for 6 months to 1 year):
amitriptyline: I was intially prescribed for migraine prevention (after taking nortriptyline years ago), but have since found and leaned on this medication to aid with several other conditions. It has significantly cut down my number of migraines making them manageable, helps mentally as I have fought mild anxiety and depression drug-free for years, and makes falling asleep and staying asleep much easier.
All that said, the first couple weeks of taking it were quite rough- slept like a dead person and was on another planet for a good 12 hours after taking it, had a horrendously dry mouth, and constantly fatigued but nearly all side effects subsided after a few weeks. Highly reccommend it to anyone fighting migraines, insomnia, or depression. Wonder drug.
43 users found this comment helpful.
amitriptyline: December 2012 was a nightmare. I get migraine average 6x a week. My migraine comes usually 30-45min after I wake up. I was taking Zomig daily for a week each took 45-2hr and a good nap to cure the pain. Heard Zomig is not for daily use so I went to doctor. Doctor prescribe me with 10mg for night time. 1st day was amazing. Migraine free. 2nd day was migraine free. However today morning I had one but less severe.
Overall - so far so good. Other than I'm 1/2 asleep throughout the day and wake up in the morning with extreme dry mouth. I hope this medication will work for me.
10 users found this comment helpful.
amitriptyline: I'm 43 and have had migraines since I was 23. I've tried everything, even preventatives (Topamax - hated it) and finally found Frova to be really effective. Then I recently got one migraine that Frova couldn't keep away for more than 12 hours. After 8 weeks of undulating pain, I tried amitriptyline and my migraine finally disappeared after only 2 days. I was also able to get a full night's sleep. Been on 10mg for two weeks now and feel almost back to my normal self again. The drowsiness subsided after about a week. I will occasionally get the sensation that I'm getting a migraine, but it dissipates quickly. No issues with weight gain yet - I actually lost about 10 pounds, but it could be because I've been doing more sleeping than eating lately.
24 users found this comment helpful.
amitriptyline: This is great at helping with my headaches! There wasn't any cause for my migraines/frequent headaches and I wanted to solve the problem. It either makes them go away completely or decreases the pain dramatically so you're able to function beautifully. However, I do get dry mouth and I feel like I have to go and pee a lot. Which are two side effects and you do get tired but mostly when it's at night when you take them so it doesn't matter too much.
15 users found this comment helpful.
Elavil (amitriptyline): I suffered with Migraines since I was about 12. I am now 36. My migraine attacks went from moderate to severe after the birth of my daughter. I would get attacks which would last for 10 days and would mimic symptoms of a stroke. I tried Sandomigran which I gained 8 kg in 3 weeks. Topamax was far worse which felt like my whole body was burning. I'm now on a combination of Zoloft 100 mg and Elavil starting at 10 mg. Generally you're not supposed to mix the 2 because it can cause "serotonin syndrome" which can be life threatening. However my neurologist and psychiatrist are keeping a close eye on me. So far Elavil has had the least side effects. I started on 10 mg and will double dose in 2 weeks. I did notice less neck and head pain.
19 users found this comment helpful.
Review by Anonymous (taken for 6 months to 1 year):
Elavil (amitriptyline): Helped my migraines a lot! However had severe constipation, gained 45lbs in 6 months, gave me night terrors and caused me to have slight depression. For migraines though it was great but due to all the side effects I was having, I have since switched. I would recommend Elavil to migraine sufferers it worked for me!
15 users found this comment helpful.
Elavil (amitriptyline): Elavil is great. I take 50 mg at night. It has helped with migraines, anxiety and depression. It is very cheap and very effective. I take it with Pristiq and Klonopin (as needed).
Review by kksf1485 (taken for 6 months to 1 year):
amitriptyline: I've had migraines for ten years now (from the age of 16) which increased in severity to the point that I was rushed to hospital with a suspected stroke. I started on amitriptyline 5mg once a day which reduced the severity of the migraines but didn't stop them altogether. I was advised that I could increase this to 20mg a day and since then (4 months) have been migraine free.
amitriptyline: I'm from the UK, and have had severe migraine for the past 20 years. They have affected not only me but my family in many ways. I don't know how they put up with it really. I have been taking 10mg at night for the past 3 months and apart from a little sleepiness in the morning it has transformed my life. My migraines initially lessened in intensity to the extent that now I just feel very tired on the days when I would have had one - this I can cope with. My regret is that I did not find out about this medicine sooner as I could have enjoyed my life and my children when they were younger more.
14 users found this comment helpful.
amitriptyline: I have been suffering from migraine from last 40 years. I used to be almost paralyzed by it everyday. My life suffered in many ways so much that I could not do many things. About 27 yrs before my College Neurologist prescribed me 10 mg amitriptyline every night and next day I would not get migraine. It was nothing less than a miracle. The side effects were also bad as last 27 yrs I fall in sleep in all those awkward places like Movie theater, While in class but I did not stop as at least I did not have migraine. No one would know the extent of migraine unless or until he/she had a first hand experience. My mouth is always dry but I will take the side effects over migraine.
Review by Kellie <3 (taken for 6 months to 1 year):
amitriptyline: I take amitriptyline for prevention of migraine with aura. The aura was so bad I couldn't function, dizziness/vertigo, facial numbness, vomiting, light sensitivity and forgetfulness/memory fog. Although I'm not back to "normal" I am able to function. I still experience dizziness from time to time and my memory isn't what it used to be but overall about 85% improvement. I have experienced some weight gain from craving sweets and other junk. Also the first month I was very tired but that stopped. I'm afraid to try something else because I fear the symptoms returning.
Elavil (amitriptyline): I took it for 6 weeks. First week 25mg increased to 50mg second week. After 10 days I didn't have a single headache. I loved that! After months of headaches 70% of the day and 2-4 migraines a week it seemed heaven sent. Only thing is it put me into a deep depression. So now I can't take Elavil. Trying Topamax 75mg and its not cutting it. Back to frequent headaches 70% of the day!
Elavil (amitriptyline): I had daily migraines for several years. I have been prescribed many different preventatives but was taking 50mg of Imitrex and 4 Tylenol #3 a day for pain relief.
Since my neurologist started me on Elavil at 25 mg and finally building up to 50 mg a night (2 months ago) I have only used 2 Imitrex and no more Tylenol with Codeine. This is truly miraculous! The only down side is a 10 lb weight gain. I eat a pretty restricted diet to begin with (no butter or fats, lean meats/fish and no sweets or snack foods). I am trying to further reduce my caloric intake to stop the weight gain. Anyway, I would rather be a little chubby and almost pain free.
10 users found this comment helpful.
amitriptyline: I have had migraines since I was a child. Tired of living in pain and having many imobilizing days, at 24 years old I finally sought treatment. I have been taking Amitriptyline for a year, starting at 15mg once every night before bed which did not seem to manage them very well, then increasing to 75mgs before bed. It has worked wonders in managing my migraines. I went from 4 migraines a week to now once a week. I will be returning to Dr. to figure out the next step since I have been a year in overall peace but still have the constant one a week. Only side effect I have noticed is slight weight gain but nothing serious. Amitriptyline has been an enormous aid in my migraine prevention and I am extremely glad to have given it a chance.
Elavil (amitriptyline): Did a decent job of preventing migraines and shortening their duration. Couldn't take full dose as it made me zombie like for a full 24 hours. Also made my heart rate 20-30bpm faster than normal.
Review by Anonymous (taken for less than 1 month):
amitriptyline: I was assigned this medicine to prevent chronic migraines, which I've been suffering from for about 15 years now. I was given a 25mg once a day at bedtime. I took it ONCE. The following day (yesterday) I couldn't feel anything. Physical or otherwise. I was a zombie. I looked at my children and husband and felt nothing, touched a very hot coffee cup and it didn't register properly. I knew I was touching it and that it was hot but it didn't cause the sensation of pain or heat. I called my doctor simply because I knew that it was something I should do, not because I actually felt I had to. I spoke in a monotone almost the whole day, slurred, and my face was an expressionless mask. Needless to say I'm not on it anymore.
Elavil (amitriptyline): I was very tired the first week, but after pushing through it I felt better. Headaches took about 2-3 weeks to go away, but they were gone. I had been having headaches almost daily and they were getting severe. I felt pain free, HOWEVER, I felt like my IQ had dropped about 20 points. I couldnt think of things quickly anymore and it was getting worse. My typing was getting worse and I was forgetting everyday things like family members names. I pulled backwards out of my driveway one day and with myself turned around looking out the rear window, I couldnt orient myself to figure out which side of the road to be on. I was on Elavil for almost 2 months. I took myself off 1 week ago. Headaches are coming back, but my memory is returning
11 users found this comment helpful.
Elavil (amitriptyline): I was previously on Cymbalta, 60mg daily, for migraine prevention. I liked it and had minimal side effects. I lost my job and am now only on Tricare so the doctor put me on Elavil, 10mg. He told me to increase the dose by 10mg every four days. I was drowsy on 10mg and a little less drowsy at 20mg. As soon as I increased to 30mg I couldn't sleep and felt shakey during the day. I tried it for four nights and, after about 4 or less hours of sleep each night, I reduced the dose to 20mg. I noticed my neck pain decreased at the 30mg but I can't function without any sleep. I have had two migraines while on the 10 and 20mg doses of this medication. SSRIs usually make me hyper and get insomnia so I wasn't surprised.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated May 16th, 2013), Cerner Multum™ (updated May 20th, 2013), Wolters Kluwer™ (updated Apr 30th, 2013) and others. To view content sources and attributions, refer to our editorial policy.