Generic Name: pregabalin (pre-GAB-a-lin)
Brand Name: Lyrica
Pregabalin solution is used for:
Treating fibromyalgia or nerve pain caused by certain conditions (eg, shingles, diabetic nerve problems, spinal cord injury). It is also used in combination with other medicines to treat certain types of seizures. It may also be used for other conditions as determined by your doctor.
Pregabalin solution is an anticonvulsant and neuropathic pain agent. Exactly how pregabalin solution works is not known. It is thought to bind to certain areas in the brain that help reduce seizures, nerve pain, and anxiety.
Do NOT use pregabalin solution if:
- you are allergic to any ingredient in pregabalin solution
Contact your doctor or health care provider right away if any of these apply to you.
Before using pregabalin solution:
Some medical conditions may interact with pregabalin solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have heart problems (eg, congestive heart failure, an irregular heartbeat), high blood pressure, muscle problems, diabetes, or bleeding problems or low platelets
- if you have kidney problems or are on dialysis
- if you have a history of mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or drug abuse
- if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or unusual hoarseness)
- if you plan to father a child
Some MEDICINES MAY INTERACT with pregabalin solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of angioedema may be increased
- Benzodiazepines (eg, lorazepam) or narcotic pain medicines (eg, oxycodone) because the risk of drowsiness may be increased
- Thiazolidinedione antidiabetic agents (eg, rosiglitazone) because the risk of weight gain or swelling of the hands and feet may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if pregabalin solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use pregabalin solution:
Use pregabalin solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Pregabalin solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get pregabalin solution refilled.
- Take pregabalin solution by mouth with or without food.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Taking pregabalin solution at the same time each day will help you remember to take it.
- Take pregabalin solution on a regular schedule to get the most benefit from it.
- If you miss a dose of pregabalin solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use pregabalin solution.
Important safety information:
- Pregabalin solution may cause drowsiness, dizziness, blurred vision, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use pregabalin solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol while you are taking pregabalin solution.
- Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking pregabalin solution; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Pregabalin solution may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Do not suddenly stop taking pregabalin solution or change your dose without checking with your doctor. If you stop taking pregabalin solution suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, anxiety, or increased sweating. If you have epilepsy and you stop taking pregabalin solution suddenly, you may have seizures more often. If you need to stop taking pregabalin solution, your dose should be gradually reduced over a period of at least 1 week.
- If you stop taking pregabalin solution for any reason, contact your doctor right away. Do not start taking it again unless your doctor tells you to. Discuss any questions or concerns with your doctor.
- If you develop new or worsening seizures, contact your doctor right away.
- Patients who take pregabalin solution may be at increased risk of suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take pregabalin solution closely. Contact the doctor at once if new, worsened, or sudden symptoms (eg, depressed mood; anxious, restless, or irritable behavior; panic attacks; any unusual change in mood or behavior) occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Tell your doctor or dentist that you take pregabalin solution before you receive any medical or dental care, emergency care, or surgery.
- Diabetes patients - Monitor your skin closely for any new or unusual sores while you take pregabalin solution.
- In animal studies, birth defects were seen in the babies of male animals who were treated with pregabalin solution. It is not known if this may also occur in humans. If you are planning to father a child, discuss the possible risks with your doctor.
- Use pregabalin solution with caution in the ELDERLY; they may be more sensitive to its effects.
- Pregabalin solution should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pregabalin solution while you are pregnant. It is not known if pregabalin solution is found in breast milk. Do not breast-feed while taking pregabalin solution.
Possible side effects of pregabalin solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Blurred vision; changes in sexual function; constipation; dizziness; drowsiness; dry mouth; headache; increased appetite; light-headedness; tiredness; trouble concentrating; weakness; weight gain.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue, unusual hoarseness); burning, numbness, or tingling; chest pain; confusion; fast or irregular heartbeat; fever, chills, or persistent sore throat; inability to control urination; loss of coordination; memory loss; muscle aches, pain, tenderness, or weakness (especially if this occurs with a fever or general feeling of discomfort); new or unusual skin sores; new or worsening mental or mood changes (eg, anxiety, depression, restlessness, irritability, panic attacks, feeling "high," behavior changes, suicidal thoughts or attempts); new or worsening seizures; reddened, blistered, swollen, or peeling skin; shortness of breath or wheezing; speaking problems; sudden, unexplained weight gain; swelling of the hands, feet, or ankles; tremor; trouble sleeping; trouble walking; unusual bruising or bleeding; severe or persistent tiredness or weakness; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of pregabalin solution:
Store pregabalin solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep pregabalin solution out of the reach of children and away from pets.
- If you have any questions about pregabalin solution, please talk with your doctor, pharmacist, or other health care provider.
- Pregabalin solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take pregabalin solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pregabalin solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pregabalin solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pregabalin solution.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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