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benazepril

Pronunciation

Generic Name: benazepril (ben AY ze pril)
Brand Name: Lotensin

What is benazepril?

Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Benazepril is used to treat high blood pressure (hypertension).

Benazepril may also be used for purposes not listed in this medication guide.

What is the most important information I should know about benazepril?

Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

If you have diabetes, do not use benazepril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

What should I discuss with my healthcare provider before taking benazepril?

You should not use this medication if you are allergic to benazepril or to any other ACE inhibitor, such as captopril, fosinopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.

If you have diabetes, do not use benazepril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

You may also need to avoid taking benazepril with aliskiren if you have kidney disease.

To make sure benazepril is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis);

  • liver disease;

  • diabetes; or

  • any history of heart disease.

FDA pregnancy category D. Do not use benazepril if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking benazepril.

Benazepril can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using benazepril.

Do not give this medicine to a child younger than 6 years old without medical advice.

How should I take benazepril?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take benazepril with or without food.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking benazepril.

Drink plenty of water each day while you are taking this medication.

Your blood pressure will need to be checked often, and you may need frequent blood tests.

If you need surgery, tell the surgeon ahead of time that you are using benazepril. You may need to stop using the medicine for a short time.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking benazepril?

Drinking alcohol can further lower your blood pressure and may increase certain side effects of benazepril.

Do not use salt substitutes or potassium supplements while taking benazepril, unless your doctor has told you to.

Benazepril side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • little or no urinating;

  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);

  • fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing; or

  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • cough;

  • headache; or

  • drowsiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Benazepril dosing information

Usual Adult Dose for Hypertension:

Initial dose: 10 mg orally once a day, in patients not receiving a diuretic.
Maintenance dose: 20 to 40 mg/day orally in 1 to 2 divided doses.
Some patients appear to have a further response to 80 mg, but experience with this dose is limited.

Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 10 mg orally once a day (5 mg if on a diuretic).
Maintenance dose: 20 to 40 mg per day orally in 1 to 2 divided doses.
Dosage may be titrated upward every 3 days.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 10 mg orally once a day (5 mg if volume depleted or hypotensive).
Maintenance dose: 20 to 40 mg orally per day in 1 to 2 divided doses.
Dosage should be increased, over a 3 day or longer period, to a dose that is maximal and tolerated but not exceeding 40 mg/day.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 10 mg orally once a day (5 mg if volume depleted or hypotensive).
Maintenance dose: 20 to 40 mg orally per day in 1 to 2 divided doses.
Dosage should be increased, over a 3 day or longer period, to a dose that is maximal and tolerated but not exceeding 40 mg/day.

What other drugs will affect benazepril?

Other drugs may interact with benazepril, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about benazepril.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 9.01. Revision Date: 2013-11-26, 2:23:53 PM.

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