Oxybutynin extended-release tablets

Pronunciation

Generic Name: oxybutynin (OX-i-BUE-ti-nin)
Brand Name: Ditropan XL

Oxybutynin extended-release tablets is used for:

Treating overactive bladder with symptoms of an urgent need to urinate, a need to urinate often, or leakage of urine. It may also be used in certain children with overactive bladder muscle (detrusor) caused by certain conditions (eg, spina bifida). It may also be used for other conditions as determined by your doctor.

Oxybutynin extended-release tablets is an anticholinergic. It works by relaxing muscles in the bladder.

Do NOT use oxybutynin extended-release tablets if:

  • you are allergic to any ingredient in oxybutynin extended-release tablets
  • you have bladder blockage or are unable to urinate
  • you have certain stomach or bowel problems (eg, blockage, decreased muscle movement)
  • you have uncontrolled narrow-angle glaucoma
  • you are taking a solid oral potassium product (eg, tablet)
  • you cannot swallow the tablet whole

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: How to Manage Your Overactive Bladder

Before using oxybutynin extended-release tablets:

Some medical conditions may interact with oxybutynin extended-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have trouble urinating or a weak urine stream
  • if you have a history of heart problems (eg, heart failure, fast or irregular heartbeat), high blood pressure, nervous system problems, liver or kidney problems, myasthenia gravis, an enlarged prostate, an overactive thyroid, esophagus problems (eg, reflux disease, inflammation, narrowing), stomach or bowel problems (eg, blockage, colitis, inflammation, constipation), or a hiatal hernia
  • if you have a history of glaucoma or increased pressure in the eyes, or if you are at risk of glaucoma (eg, family history of glaucoma)
  • if you will be exposed to high temperatures for a long period of time
  • if you have very poor health or you have a history of alcohol abuse
  • if you are taking a cholinesterase inhibitor (eg, donepezil) to treat dementia. Ask your doctor or pharmacist if you are not sure

Some MEDICINES MAY INTERACT with oxybutynin extended-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Bisphosphonates (eg, alendronate) because the risk of irritation of the esophagus may be increased
  • Other anticholinergic medicines (eg, scopolamine), azole antifungals (eg, ketoconazole), or macrolide antibiotics (eg, erythromycin) because they may increase the risk of oxybutynin extended-release tablets's side effects
  • Solid oral potassium products (eg, tablets) because the risk of stomach or bowel irritation may be increased by oxybutynin extended-release tablets
  • Phenothiazines (eg, chlorpromazine) because their effectiveness may be decreased by oxybutynin extended-release tablets and they may increase the risk of oxybutynin extended-release tablets's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if oxybutynin extended-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use oxybutynin extended-release tablets:

Use oxybutynin extended-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take oxybutynin extended-release tablets by mouth with or without food.
  • Swallow oxybutynin extended-release tablets whole. Do not break, crush, or chew before swallowing.
  • Take oxybutynin extended-release tablets with a full glass of water (8 oz [240 mL]).
  • Take oxybutynin extended-release tablets on a regular schedule to get the most benefit from it. Oxybutynin extended-release tablets works best if it is taken at the same time each day.
  • Continue to take oxybutynin extended-release tablets even if you feel well. Do not miss any doses.
  • If you miss a dose of oxybutynin extended-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use oxybutynin extended-release tablets.

Important safety information:

  • Oxybutynin extended-release tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use oxybutynin extended-release tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using oxybutynin extended-release tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Oxybutynin extended-release tablets may cause decreased sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur. Contact your doctor if you have been exposed to high temperatures and you develop fever; flushing; hot, dry skin; severe or persistent headache; dizziness; sudden fatigue; fast heartbeat; seizures; or fainting.
  • Oxybutynin extended-release tablets may cause dry mouth. To help relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Ask your doctor or pharmacist if you have any questions.
  • Oxybutynin extended-release tablets may cause a serious side effect called angioedema. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.
  • You may notice the tablet shell in your stool. This is normal and not a cause for concern.
  • Use oxybutynin extended-release tablets with caution in the ELDERLY; they may be more sensitive to its effects.
  • Oxybutynin extended-release tablets should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if oxybutynin extended-release tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking oxybutynin extended-release tablets while you are pregnant. It is not known if oxybutynin extended-release tablets is found in breast milk. If you are or will be breast-feeding while you take oxybutynin extended-release tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of oxybutynin extended-release tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; diarrhea; dizziness; drowsiness; dry eyes, nose, skin, or mouth; headache; indigestion; nausea; stomach upset; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); confusion; difficult or painful urination; fast or irregular heartbeat; fever; hallucinations; mental or mood changes (eg, agitation, depression); seizures; severe or persistent constipation or stomach pain; swelling of the hands, ankles, or feet; vision problems.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; coma; confusion; delirium; enlarged pupils; fever; flushing; hallucinations; inability to urinate; irregular heartbeat; irritability; memory problems; paralysis; restlessness; seizures; severe or persistent dizziness, drowsiness, or headache; tremor; trouble breathing; unusually dry mouth or skin; vomiting.

Proper storage of oxybutynin extended-release tablets:

Store oxybutynin extended-release tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep oxybutynin extended-release tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about oxybutynin extended-release tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Oxybutynin extended-release tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take oxybutynin extended-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about oxybutynin extended-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to oxybutynin extended-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using oxybutynin extended-release tablets.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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