Generic Name: estramustine (ess-tra-MUSS-teen)
Brand Name: Emcyt
Estramustine is used for:
Treating prostate cancer.
Estramustine is an antineoplastic. It works by interfering with production of necessary proteins for tumor cell growth and reproduction.
Do NOT use estramustine if:
- you are allergic to any ingredient in estramustine
- you are allergic to either estradiol or nitrogen mustard
- you have vein inflammation or disorders that block blood vessels (eg, blood clots), unless the actual tumor mass is the cause of the blockage and your doctor feels the benefits of therapy may outweigh the risks
- you are a woman
Contact your doctor or health care provider right away if any of these apply to you.
Before using estramustine:
Some medical conditions may interact with estramustine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have problems with blood vessels in your brain (cerebral vascular disease) or heart (cardiovascular disease)
- if you have diabetes or heart disease
Some MEDICINES MAY INTERACT with estramustine. However, no specific interactions with estramustine are known at this time.
This may not be a complete list of all interactions that may occur. Ask your health care provider if estramustine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use estramustine:
Use estramustine as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the label on the medicine for exact dosing instructions.
- Take estramustine on an empty stomach at least 1 hour before or 2 hours after meals.
- Swallow estramustine with water.
- Do not take antacids containing calcium, or eat or drink dairy products within 1 hour before or 2 hours after taking estramustine.
- If nausea, vomiting, or loss of appetite occurs, ask your doctor or pharmacist for ways to lessen these effects.
- Several days to weeks may pass before you feel the full benefit of estramustine. Do not stop taking estramustine without checking with your doctor.
- If you miss a dose of estramustine, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use estramustine.
Important safety information:
- Diabetes patients - Estramustine may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
- Estramustine may alter the results of some lab tests, including liver function tests, and bilirubin and testosterone blood levels. Be sure all of your doctors and lab personnel know that you are taking estramustine.
- Both men and women should use effective birth control methods while using estramustine.
- PREGNANCY and BREAST-FEEDING: Do not use estramustine if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. If you are or will be breast-feeding while you are using estramustine, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of estramustine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Anxiety; breast enlargement or tenderness; bruising; chest pain; diarrhea; hair thinning; headache; hoarseness; leg cramps; loss of appetite; mood swings; nausea; sleep loss; sore throat; stomach ache; vein inflammation; watery eyes.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; chest pain; easy bruising; impotence; numbness of an arm or leg; stroke; sudden leg pain; sudden, severe headache; swelling of the feet or ankles.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of estramustine:
Store estramustine in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Keep estramustine out of the reach of children and away from pets.
- If you have any questions about estramustine, please talk with your doctor, pharmacist, or other health care provider.
- Estramustine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take estramustine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about estramustine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to estramustine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using estramustine.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.