Also known as: Eligard, Lupron, Lupron Depot, Lupron Depot-Gyn, Lupron Depot-Ped
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Lupron Depot (leuprolide) for Endometriosis: I was very pleased with my Lupron experience. I was on a six month course and found the first three to four months easy. I did experience hot flashes, mood swings, and slight insomnia. My fifth and sixth month were a little more difficult for me. The hot flashes became a little more apparent, the mood swings more frequent, and my face began to break out. To me, that was the worst. Along with the Lupron, I had a laproscopy 2 months before the medication and I started acupuncture treatments about a month before beginning Lupron which really helped with the side effects. My pain levels before medication were unbearable. I could hardly bring myself to get out of bed. I now notice that my pain level is low if I have any at all.
0 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Endometriosis: I just had my second shot 6 days ago. I will admit that my pain from the endo is a great deal better than it was. I was a few days late to get my 2nd shot and could feel the symptoms coming back slowly. The side effects are miserable. I don't want to finish out the treatment. Going for a second opinion. Will be trying estradiol today, for the hot flashes, which have been the worst, at least 3 an hour, and all night long. Haven't had any weight gain so far, weight loss, probably because I am so paranoid about gaining.
1 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Endometriosis: The drug seems to be helping, but the side effects are bad. I am experiencing every one of them and the hot flashes are constant. It will only be worth it if the pain from the Endometriosis is gone.
1 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Prostate Cancer: I've been on Lupron (after prostae surgery) for a period of 7-1/2 years. I am also on 50mg Casosex. The side effects are minor (hot sweats, decreased energy) Injection site(s) were moved after 6 yrs. from buttox to shoulder(s) due to lower back pain. I hope this gives hope to patients about to begin this regimen.
4 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Endometriosis: I got my first shot almost two weeks ago. I am fat, busty and generally unmotivated. I am a tiny bit nauseous almost all of the time, but it's not bad enough to prevent me from eating. More like an appetite suppressant. Other than that everything seems fine. Although I have stage 4 endometriosis, I didn't have any of the associated symptoms, except for infertility. I guess I'll find out in a year or two if it is worth it.
3 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Endometriosis: I took my first injection 4 days ago, but had a migraine that night. Since then I have been crying a lot. I can't believe the side effects have hit me so fast. I have abdominal pain as well but the crying is the worst so far.
5 user(s) found this comment helpful. Did you?YesNo
Lupron Depot-PED (leuprolide) for Precocious Puberty: My daughter was diagnosed with CPP at 2 years old, the pubic hair and breast development disappeared by changing to an all organic diet even before starting the treatment. She still has mood swings and her height has improved with the lupron, but the doctor still can't give me a cause or hope of when we'll stop the vaccine.
0 user(s) found this comment helpful. Did you?YesNo
Lupron Depot-PED (leuprolide) for Precocious Puberty: I have extreme mixed feelings about this drug. At the age of 5, I was diagnosed with Precocious Puberty. My endocrinologist suggested I start Lupron, and I did. It did exactly what it was supposed to do.. I quit growing taller, and stopped puberty-like symptoms. One problem- I did not grow taller, but I was still eating. I gained a lot of weight, but the doctors promised that once I quit the shots everything would even out. I quit the shots after 7 years of treatment, and it did not "even out". The weight gain caused Insulin Resistance, which also played with my hormones, and led to Polycystic Ovarian Syndrome.
2 user(s) found this comment helpful. Did you?YesNo
Lupron (leuprolide) for Prostate Cancer: While I do believe it has lengthened by life, the side effects are difficult to deal with. I am extremely sun sensitive, also have a rash on my wrists that doesn't go away.
11 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Endometriosis: I am on my 2nd shot of Lupron and I am not liking the new me. Everyone says after the first 6 weeks it gets better. I don't know if I can take anymore or if anyone else can take my mood swings. I am very hormonal, frustrated all the time and mad about everything. My job and family are suffering. The hot flashes are constant I am miserable. I don't think I will continue with the other shots.
10 user(s) found this comment helpful. Did you?YesNo
Lupron Depot-PED (leuprolide) for Precocious Puberty: My daughter than 3 1/2 now 6 1/2 started the Lupron 7.25mg every 3 weeks. She did have a small side effect of hot flashes and eating ups and downs. This medication did take awhile for her blood estogen levels to even out but the medication worked as it should have. We hope to stop the Lupron if all goes well. If not we still have another 5 years or so of the shots.
1 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Endometriosis: I have taken monthly injections for the past 6 months. I had a very difficult time for the first 6 weeks of treatment, but since then have not had many side effects. I had severe stomach cramping initially, along with migraines and mood swings. As those side effects subsided, the hot flashes began. With the hot flashes came nausea and unpredictable crying fits. My doctor put me on a low dose of Estradiol and Prozac. Within a few days, I was pretty much back to my old self, minus the horrible belly pains. I have to say overall the good outweighs the bad.
7 user(s) found this comment helpful. Did you?YesNo
leuprolide for Precocious Puberty: My daughter has been on Lupron for 2 1/2 years now, she started at age 4. We have had success in stopping the symptoms of puberty. The side effects that we have encountered which have now stopped are the hot flashes and eating cravings and binges. We do have to continue with the injection every three weeks, but up to this point it has been well worth it.
0 user(s) found this comment helpful. Did you?YesNo
Lupron Depot-PED (leuprolide) for Precocious Puberty: My 8 year old daughter has been diagnosed with precocious puberty. While being proactive about the whole issue of stunted growth and and early menses etc., We (my husband and I) were in the process of setting up an appointment to have her initial injection of the drug, lupron depot-PED and guess what?...she started her first menstrual cycle. We still went ahead with the treatment as planned. We are three treatments into the whole plan and things are going well but there is a side effect that has lingered hot flushes that are still waking her up during the night.
3 user(s) found this comment helpful. Did you?YesNo
Lupron Depot-PED (leuprolide) for Precocious Puberty: As a child I encountered precocious puberty, at the age of 8. My pediatrician then referred me to my endocrinologist. She suggested the vaccine to stop my puberty so I could grow, if not I would end up being shorter than 5 feet. Now I'm 5'1 1/2, if it was not for this vaccine I would not even have reached 5 feet. I am thankful for her, and for my parents that put me through this four-year process of daily injections. It was a long ride, but it was worth it at the end.
6 user(s) found this comment helpful. Did you?YesNo
Lupron Depot (leuprolide) for Endometriosis: The shot is not too bad in the butt cheek. My problems were the side effects. I think that the hot flashes are the worst of it. I am on my 5th shot, and now I am going through a lot of mood swings as well.
24 user(s) found this comment helpful. Did you?YesNo
mike190 said: 
