Also known as: Eligard, Lupron, Lupron Depot, Lupron Depot 11.25 mg, Lupron Depot 3.75 mg, Lupron Depot-Gyn, Lupron Depot-PED, Viadur
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Lupron (leuprolide) for Prostate Cancer: While I do believe it has lengthened by life, the side effects are difficult to deal with. I am extremely sun sensitive, also have a rash on my wrists that doesn't go away.
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Lupron (leuprolide) for Prostate Cancer: I have been receiving Lupron or Eligard every 6 months for ten years to help reduce the growth of prostate cancer. Early research reports indicated that one side effect might be peripheral neuropathy. That started to develop in my feet shortly after I was put on Lupron. Loss of bone mass has also been associated with Lupron. I have begun taking 1200 units of calcium VitaminD each day. My PSA scores have all continued to be below .1. I have no major complaints, and have learned to live with the side effects.
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Lupron (leuprolide) for Endometriosis: I just finished my 3 month course of shots. The first two months were not to bad but the third month has taken its toll on me. I can deal with the hot flashes but the joint pain has become very intense. The pain is disruptive where my hands are aching all the time. It keeps me up at night time then lack of sleep becomes a problem. I wish they would suggest a joint therapy program for you to take if you need because its not like you can just call up your doctor and see him right away.
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Lupron Depot (leuprolide) for Endometriosis: The shot is not too bad in the butt cheek. My problems were the side effects. I think that the hot flashes are the worst of it. I am on my 5th shot, and now I am going through a lot of mood swings as well.
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Lupron Depot (leuprolide) for Prostate Cancer: I've been on Lupron (after prostae surgery) for a period of 7-1/2 years. I am also on 50mg Casosex. The side effects are minor (hot sweats, decreased energy) Injection site(s) were moved after 6 yrs. from buttox to shoulder(s) due to lower back pain. I hope this gives hope to patients about to begin this regimen.
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Lupron (leuprolide) for Uterine Fibroids: Side effects experienced from 3-month shot: hot flashes, night sweats, fatigue, cognitive "fuzziness", decreased memory. I experienced a significant temporary reduction in fibroid size/abdomen size (pre-surgery).
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Lupron Depot (leuprolide) for Endometriosis: I am on my 2nd shot of Lupron and I am not liking the new me. Everyone says after the first 6 weeks it gets better. I don't know if I can take anymore or if anyone else can take my mood swings. I am very hormonal, frustrated all the time and mad about everything. My job and family are suffering. The hot flashes are constant I am miserable. I don't think I will continue with the other shots.
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Lupron Depot (leuprolide) for Endometriosis: I have taken monthly injections for the past 6 months. I had a very difficult time for the first 6 weeks of treatment, but since then have not had many side effects. I had severe stomach cramping initially, along with migraines and mood swings. As those side effects subsided, the hot flashes began. With the hot flashes came nausea and unpredictable crying fits. My doctor put me on a low dose of Estradiol and Prozac. Within a few days, I was pretty much back to my old self, minus the horrible belly pains. I have to say overall the good outweighs the bad.
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Lupron Depot (leuprolide) for Uterine Fibroids: I can't say enough about how glad I am that I was given Lupron injections! I was being treated for heavy non-stop bleeding caused by the several large fibroids I had. I was told by 3 different Doctor's that I would definitely need to have a hysterectomy. I really had no other option. My OBGYN and the surgeon, started me on the Lupron injections 4 months ago to stop the bleeding (I had become extremely anemic and couldn't have the surgery until my blood counts came back up which would take 3 months) and to try and shrink the fibroids. After my 4th and final shot 2 weeks ago, my MRI showed that the fibroids had shrunk 75% and my surgeon discharged me today saying that I will NOT be having a hysterectomy, nor any surgery! Thank you Lupron.
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Lupron (leuprolide) for Prostate Cancer: Second injection started night and day sweats. This has increased to every 2-3 hrs during the day - less frequency at night. Dropped my PSA from 30 to .07 post prostate removal. Time on medication - 6 months.
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Lupron Depot (leuprolide) for Endometriosis: I took my first injection 4 days ago, but had a migraine that night. Since then I have been crying a lot. I can't believe the side effects have hit me so fast. I have abdominal pain as well but the crying is the worst so far.
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Eligard (leuprolide) for Prostate Cancer: I was given two injections of Elgard before beginning radiation therapy. Following the
48 radiation treatments, I am still being monitored by my oncologist and urologist. My last PSA was 0.01. The side effects of hot flashes, lethargy, and muscle weakness are where I am today, although at my age, 79, I can't complain. The first of the injections was in April of 2008 and the second in August. Radiation began in early September 2008 and ended at end of October.
It was determined that I am not a candidate for Androgel as there is a possibility of developing cancer again. So, as you read from the preceding paragraph, I'm lucky
to have passed my first year without problems.
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Lupron Depot-PED (leuprolide) for Precocious Puberty: As a child I encountered precocious puberty, at the age of 8. My pediatrician then referred me to my endocrinologist. She suggested the vaccine to stop my puberty so I could grow, if not I would end up being shorter than 5 feet. Now I'm 5'1 1/2, if it was not for this vaccine I would not even have reached 5 feet. I am thankful for her, and for my parents that put me through this four-year process of daily injections. It was a long ride, but it was worth it at the end.
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Lupron (leuprolide) for Endometriosis: This is my fourth month into the Lupron cycle. I have endometriosis. Have no period, NO PAIN. I do get some hot flashes and a little weight gain but that is the least of my problems on the shot. It is the joint pain. It is the worst in the morning when I get out of bed. My hands, legs and feet are the worst. It is not so bad throughout the day. But when I sit for sometime then get up again the pain starts all over.
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Lupron Depot (leuprolide) for Endometriosis: I was very pleased with my Lupron experience. I was on a six month course and found the first three to four months easy. I did experience hot flashes, mood swings, and slight insomnia. My fifth and sixth month were a little more difficult for me. The hot flashes became a little more apparent, the mood swings more frequent, and my face began to break out. To me, that was the worst. Along with the Lupron, I had a laproscopy 2 months before the medication and I started acupuncture treatments about a month before beginning Lupron which really helped with the side effects. My pain levels before medication were unbearable. I could hardly bring myself to get out of bed. I now notice that my pain level is low if I have any at all.
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Lupron (leuprolide) for Breast Cancer, Adjuvant: After surgery and radiation therapy, I was unable to take Tamoxifen, so I got a 1-month shot of Lupron to prevent a recurrence of breast cancer. I had no symptoms, so I got the 3-month shot and immediately had problems. I expected the bad hot flashes and dryness, but wasn't prepared for the severe bone pain and muscle pain. I'm used to dealing with pain, but this was extreme. By the end of the 3-mos, the bone pain was gone, but the muscle pain and injection site soreness was still there. I got another 1-mo shot and have been doing better. Now I have unexplained swelling/soreness in my left hand.
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Lupron Depot (leuprolide) for Uterine Fibroids: I just received my 2nd shot of 3.75 Lupron and so far so good! I have heard horror stories not only on line, but from my friends who have been on it for various reasons and I was more than worried to start it. I have one large fibroid and I was put on Lupron injections to shrink it to make it easier for my husband and I to have a baby after I have a robotic myomectomy in June. I was so afraid of mood swings, but surprisingly, after 5 weeks I am still very happy. My bloating has gone away for the most part and I am really looking forward to not bleeding the way I did due to this fibroid! All in all, I am posting on here so that woman like myself, a 35 year old wanting a baby will know that not all Lupron horror stories will happen to you!
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Lupron Depot (leuprolide) for Endometriosis: I did a 6 month treatment of Lupron and It wasn't that bad. The first couple of months I experienced migraines & hot flashes. For the reminder or the treatment, I continued to experience the hot flases but my mood swings became very uncomfortable for my family, friends, & me. I would one minute be calm & neutral...the next minute I would become mean & hateful. That was never how I was prior to the treatment. However, I completed my treatment in August 2009 and I haven't had any problems with my endometriosis at all. My doctor has now given me the option to either get pregnant or continue with birth control pills until I decide to become pregnant to maintain the endometriosis. I highly recommend this method if you can withstand the side effects.
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Lupron Depot (leuprolide) for Uterine Fibroids: I love that it completely stopped my outrageous heavy bleeding, which in turn made me anemic. So I am happy for that. However, the only side effect that I am experiencing is super dry skin on my arms, neck and face...I feel it is aging me overnight. Some constipation, and not really hot flashes but warm spells every now and then. Can't wait for surgery to get my hormones back to work.
Lupron Depot (leuprolide) for Endometriosis: At first I really thought the Lupron treatments where worth it, but now that I have made a trip to the Emergency Room. Well lets just say if you are going to go the route of Lupron you better be single. This drug takes its toll on the family, not just you. Everyone goes throw the mood swings, headaches, blood pressure scares, joint pain, feeling like you are going to pass out. So no taking your kids to school or sporting events. No joining car pools. Don't get to far away from the restroom, urinating more often is not unusual. The things that are the easiest to handle are the hot flashes, night sweats and chills.
Lupron (leuprolide) for Endometriosis: I started the Lupron at the beginning of the summer, April 2011 to be exact. The only side effect I can say I had trouble with was the hot flashes but nothing unbearable and usually over pretty quick. The first 3-4 weeks after an injection, I would have issues with vaginal dryness but again, nothing unbearable. I had no mood swings or crazy headaches but I have been constantly plagued with headaches since I was a child so I wouldn't know if this had any effect on those. Overall, it has been a totally bearable experience and the hot flashes were nothing compared to the pain I had before the Lupron. I would suggest it if your endometriosis is bad enough.
Lupron Depot-PED (leuprolide) for Precocious Puberty: I have extreme mixed feelings about this drug. At the age of 5, I was diagnosed with Precocious Puberty. My endocrinologist suggested I start Lupron, and I did. It did exactly what it was supposed to do.. I quit growing taller, and stopped puberty-like symptoms. One problem- I did not grow taller, but I was still eating. I gained a lot of weight, but the doctors promised that once I quit the shots everything would even out. I quit the shots after 7 years of treatment, and it did not "even out". The weight gain caused Insulin Resistance, which also played with my hormones, and led to Polycystic Ovarian Syndrome.
Lupron Depot (leuprolide) for Endometriosis: I just had my 5th shot yesterday. The past few months have been painless in regards to side effects other then night sweats and mood swings. I have not gained any weight and everything seems pretty normal. Once again, other than the mood swings. These are harsh and sometimes I feel like another person has taken over my body and thoughts.
Lupron (leuprolide) for Endometriosis: I have been on the Lupron shot now 5 months. I have had no periods or period associated pain since the second month. There is some minor pain and irritation at the injection site for a day or two after the shot. I have had pretty intense hot flashes and night sweats, minor joint and muscle pain, but the worst for me has been the massive headaches. I am taking another medication now to help with those. I would still recommend the shot if your endometriosis is severe, the side effects still aren't as bad as the pain I was in before. Trying to hang in there for another 4 months.
May 21, 2012 -- Medivation
Inc. and Astellas Pharma Inc.
announced that Medivation has submitted a New Drug Application
(NDA) to the U.S. Food and Drug...
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