Estramustine Dosage
This dosage information may not include all the information needed to use Estramustine safely and effectively. See additional information for Estramustine.
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Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Prostate Cancer
Initial Dose: 14 mg per kg daily, given in 3 or 4 divided doses.
Patients should be treated for thirty to ninety days before the physician determines the possible benefits of continued therapy. Therapy should be continued as long as the favorable response lasts. Some patients have been maintained on therapy for more than three years at doses ranging from 10 to 16 mg per kg of body weight per day.
Patients should be instructed to take estramustine capsules at least 1 hour before or 2 hours after meals. Estramustine capsules should be swallowed with water. Milk, milk products, and calcium-rich foods or drugs (such as calcium-containing antacids) must not be taken simultaneously with estramustine.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).
Dialysis
Data not available
