Skip to Content

GRIPPOSTAD DAY CAPSULES

Active substance(s): CAFFEINE / PARACETAMOL / PHENYLEPHRINE HYDROCHLORIDE

View full screen / Print PDF » Download PDF ⇩
Transcript
UK/H/4922/001/II/005

2015-10-15

Package leaflet: Information for the user
Grippostad Day Capsules
Paracetamol, caffeine, phenylephrine hydrochloride
Read all of this leaflet carefully before you start taking this medicine because it
contains important information for you.
Always take this medicine exactly as described in this leaflet or as your doctor or
pharmacist have told you.
- Keep this leaflet. You may need to read it again.
- Ask your pharmacist if you need more information or advice.
- If you get any side effects, talk to your doctor or pharmacist. This includes any possible
side effects not listed in this leaflet. See section 4
- You must talk to a doctor if you do not feel better or if you feel worse after 3 days.
What is in this leaflet
1. What Grippostad Day is and what it is used for
2. What you need to know before you take Grippostad Day
3. How to take Grippostad Day
4. Possible side effects
5. How to store Grippostad Day
6. Contents of the pack and other information

1. What Grippostad Day is and what it is used for
Grippostad Day contains three drugs to help treat your symptoms (active ingredients):
 Paracetamol, which is an analgesic (pain killer) and antipyretic (it reduces body
temperature when you have a fever)
 Phenylephrine, which is a type of drug known as a sympathomimetic. This works as a
decongestant by unblocking the passages in and around your nose. This helps you to
breathe more easily.
 Caffeine, which acts to further help the effectiveness of paracetamol.
Grippostad Day is used to relieve the symptoms of colds and influenza (flu) including fever,
aches and pains, sore throat and nasal congestion.
This medicine is for use in adults and children aged 12 years and over.

2. What you need to know before you take Grippostad Day
DO NOT take Grippostad Day
 If you are allergic to paracetamol, caffeine, phenylephrine hydrochloride, or any of the
other ingredients of this medicine (listed in section 6).
 If you have a rare hereditary disease known as glucose-6-phosphate dehydrogenase
(G6PD) deficiency. G6PD deficiency is a shortage of an enzyme and can lead to
anaemia (a shortage of red blood cells).
 If you have a tumour of the adrenal glands called a phaeochromocytoma. The
adrenal glands are triangle-shaped and located on top of your kidneys.
 If you have liver problems

PIL-common

1 of 8

UK/H/4922/001/II/005











2015-10-15

If you have severe kidney problems
If you have high blood pressure
If you have a thyroid gland that is too active
If you have diabetes
If you have heart disease
If you have raised pressure in the eye (glaucoma)
If you are taking drugs known as beta blockers
If you are taking drugs for depression known as tricyclic antidepressants
If you are taking or have taken drugs for depression known as monoamine oxidase
inhibitors (MAOIs) in the last two weeks

Warnings and precautions
 If you have an enlarged prostate gland. Symptoms of an enlarged prostate gland
include difficulty urinating, painful urination, or urinating more often.
 If you have Raynaud's phenomenon (discolouration of the fingers and toes caused by
poor circulation)
 If you have heart or circulation problems
 If you are an alcoholic
You should not use Grippostad Day if you are also using other sympathomimetic drugs
(stimulants or appetite suppressants and drugs used to treat congestion and asthma).
Do not take too much caffeine (e.g. coffee, tea and some canned drinks) when you are
taking Grippostad Day.
Do not take any other medicines containing paracetamol. Taking too much
paracetamol can lead to serious liver damage which can sometimes be fatal. You should
take particular care if you have liver or kidney disease. You are more at risk of overdose if
you are an alcoholic.
You should see your doctor if:
 you develop a high fever
 you develop signs of other infection such as feeling unwell, night sweats, tiredness, pain,
or swelling
 your symptoms do not get better after three days
Other medicines and Grippostad Day
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other
medicines.
The following medicines may affect or be affected by Grippostad Day.
You should not take Grippostad Day with any of the following medicines without first talking
to your doctor:
 Monoamine oxidase inhibitors (MAOIs), including moclobemide
 Sympathomimetic drugs (stimulants or appetite suppressants and drugs used to treat
congestion and asthma)
 Beta blockers and other antihypertensive drugs (used to treat high blood pressure),
including debrisoquine, guanethidine, reserpine, and methyldopa
 Tricyclic antidepressants, for example amitriptyline, used to treat feeling sad
(depression)
 Cardiac glycosides (drugs used to control heart rhythms or contractions) for example
digoxin
 Ergot alkaloids (drugs used to treat migraine), for example ergotamine and methysergide
 Anticoagulants (drugs used to thin the blood, such as warfarin)

PIL-common

2 of 8

UK/H/4922/001/II/005

2015-10-15

 Propantheline (used to treat gastrointestinal disorders, wetting (enuresis), and excessive







sweating (hyperhidrosis)
Pethidine and pentazocine (pain killers)
Metoclopramide or domperidone (used to treat nausea and vomiting)
Colestyramine (used to lower blood cholesterol)
Carbamazepine, phenobarbital, phenytoin, and primidone (used to treat epilepsy)
Rifampicin (an antibiotic)
St John's Wort (used to treat depression)

Do not take Grippostad Day with other products containing paracetamol.
Grippostad Day with drink and alcohol
Do not drink alcohol (wine, beer, spirits) whilst taking this medicine.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a
baby, ask your doctor or pharmacist for advice before taking this medicine.
Do not take this product if you are pregnant or while breast-feeding.
Driving and using machines
Take care when driving. Grippostad Day may affect your reactions, especially:
 at the start of treatment
 after increasing your dose
 when changing from a different medication
 if you also drink alcohol
Do not operate any tools or machines or drive if your reactions are affected.
Important information about some of the ingredients of Grippostad Day
 Warning:
Grippostad Day contains paracetamol and a drug to reduce congestion in the nasal
passages (decongestant). Do not take with any other product for the relief of flu, colds or
nasal congestion, or with other products containing paracetamol.

3. How to take Grippostad Day
Always take this medicine exactly as described in this leaflet or as your doctor or
pharmacist have told you. Check with your doctor or pharmacist if you are not sure.
The usual dose is:
Adults (including the elderly):
Take 2 capsules up to 4 times a day as required.
Do not take more than 8 capsules in 24 hours.
Leave at least 4 hours between doses.
Children between 12 and 18 years of age
Take 2 capsules up to 3 times a day as required.
Do not take more than 6 capsules in 24 hours.
Leave at least 4 hours between doses.
Do not take a higher dose than the recommended dose without first talking to your
doctor.

PIL-common

3 of 8

UK/H/4922/001/II/005

2015-10-15

Grippostad Day should be used during daytime only, as it contains caffeine, which
may cause sleeplessness.
How to take Grippostad Day
The capsules should be taken by mouth.
Swallow the capsules whole with water. Do not chew.
For how long should you take Grippostad Day
If your symptoms do not get better after three days, talk to your doctor.
Children under 12 years
Do not give Grippostad Day to children under 12 years old.
If you take more Grippostad Day than you should
Contact your doctor or nearest emergency department immediately for advice if:
 You accidentally take too many capsules
 A child takes any Grippostad Day
You should do this straight away even if you feel well. If you delay there is a risk of serious
liver damage. Take your medicine and this leaflet with you so that the medical staff know
what you have taken.
You are at greater risk of overdose if:
 you are taking any of the following medicines for more than a few weeks:
o carbamazepine, phenobarbital, phenytoin, and primidone (used to treat epilepsy)
o rifampicin (an antibiotic)
o St John's Wort (used to treat depression)
 you regularly drink too much alcohol
 you have a shortage of a protein called glutathione. This can be due to:
o an eating disorder such as lack or loss of appetite
o starvation, or if you lose weight even when eating normally (a body wasting disease
called cachexia)
o cystic fibrosis (a hereditary disease causing breathing difficulties)
o HIV infection (AIDS)
Symptoms of overdose in the first 24 hours are:
 Pale skin (pallor)
 Feeling sick (nausea)
 Being sick (vomiting)
 Lack of appetite (anorexia)
 Tummy pain (abdominal pain)
Other symptoms are:
 Problems with breaking down glucose
 Too much acid in the body (metabolic acidosis).
Severe overdose can be fatal and lead to:
 Liver failure
 Brain damage (encephalopathy)
 Bleeding (haemorrhage)
 Low blood sugar levels (hypoglycaemia)
 Swelling of the brain (cerebral oedema)
 Kidney failure with loin pain (acute tubular necrosis)
 Blood in the urine (haematuria)

PIL-common

4 of 8

UK/H/4922/001/II/005
















2015-10-15

Protein in the urine (proteinuria)
Irregular heartbeat (cardiac arrhythmia)
Inflamed pancreas (pancreatitis)
Pain in the upper part of the tummy (epigastric pain)
Being sick (vomiting)
Increased urine production (diuresis)
Rapid heartbeat (tachycardia)
Stimulation of the nervous system including:
o difficulty sleeping (insomnia)
o restlessness
o excitement
o feeling anxious (agitation)
o feeling nervous and flustered (jitteriness)
o uncontrolled shaking (tremors)
o fits (convulsions)
Other effects similar to those under section 4 “Possible Side Effects” in this leaflet
High blood pressure (hypertension)
Slow heartbeat (reflex bradycardia)
Confusion
Seeing or hearing things that are not there (hallucinations)

If you forget to take Grippostad Day
Do not take a double dose to make up for a forgotten capsule.
Make sure your next dose is taken at least four hours after your previous dose.
If you have any further questions on the use of this medicine, ask your doctor or
pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
If you experience any of the following stop using the medicine and seek immediate
help
 Allergic reactions:
o swelling of the skin, of the face and lips, tongue and throat, or voice box
(angio-oedema)
o difficulty breathing (dyspnoea)
o sweating
o feeling sick (nausea)
o low blood pressure (hypotension) leading to shock
o severe allergic reaction (anaphylaxis)
 Allergic skin reactions (cutaneous hypersensitivity reactions) including:
o skin rashes
o a serious illness with blistering of the skin, mouth, eyes and genitals
o severe blistering and peeling of the skin
If you experience any of the following, stop using the medicine and talk to your
doctor
 Allergic reactions, for example: rash, hives (urticaria), skin inflammation (allergic
dermatitis)
 Allergic (hypersensitivity) reactions. If you have had an allergic reaction with other

PIL-common

5 of 8

UK/H/4922/001/II/005

2015-10-15

sympathomimetic drugs (such as pseudoephedrine) before, you are more likely to have
an allergic reaction (cross-sensitivity)
Very rare (may affect up to 1 in 10,000 people):
 Very rare cases of serious skin reactions have been reported
 Liver problems (hepatic dysfunction)
Not known (frequency cannot be estimated from the available data):
 Low numbers of blood cells called platelets or thrombocytes (thrombocytopenia)
 Low numbers of white blood cells called leukocytes (leukopenia)
 A severe lack of white blood cells (agranulocytosis)
 Low numbers of red and white blood cells (pancytopenia)
 Tiredness
 Headache
 Dizziness
 Difficulty sleeping (insomnia)
 Anxiety
 Nervousness
 Feeling irritated (irritability)
 Restlessness
 Feeling excited (excitability)
 Worsening of raised pressure in the eye (pre-existing narrow-angle glaucoma) (see also
section 2. “DO NOT take Grippostad Day”)
 Dilated pupils (mydriasis)
 Sudden raised pressure in the eye (acute angle closure glaucoma)
 High blood pressure (hypertension)
 Feeling your heartbeat (palpitations)
 Rapid heartbeat (tachycardia)
 Narrowing of the upper airways (bronchospasm)
 Dry mouth
 Feeling sick (nausea)
 Being sick (vomiting)
 Runny stools (diarrhoea)
 Lack of appetite (anorexia)
 Kidney problems (renal dysfunction)
 Difficulty urinating (dysuria) or inability to urinate (urinary retention). This is more likely to
occur if your bladder is blocked, for example if you have an enlarged prostate. See also
section 2. “Warnings and precautions.”
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side
effects not listed in this leaflet. You can also report side effects directly via {to be completed
nationally: the national reporting system listed in Appendix V}. By reporting side effects, you
can help provide more information on the safety of this medicine.

5. How to store Grippostad Day
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton. The expiry date
refers to the last day of that month.

PIL-common

6 of 8

UK/H/4922/001/II/005

2015-10-15

Do not store above 25 °C.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist
how to throw away medicines you no longer use. These measures will help protect the
environment.

6. Contents of the pack and other information
What Grippostad Day contains
The active substances are:
 paracetamol
 caffeine
 phenylephrine hydrochloride
Each capsule contains:
 300 mg paracetamol
 25 mg caffeine
 5 mg phenylephrine hydrochloride
The other ingredients are:
 ascorbic acid
 glycerol tristearate
 sodium laurylsulphate
 colloidal anhydrous silica
 magnesium stearate
The other ingredients in the capsule shell are:
 gelatin
 titanium dioxide (E 171)
 yellow iron oxide (E 172)
What Grippostad Day Capsules looks like and contents of the pack
Grippostad Day Capsules are hard capsules with a white body and yellow cap.
Grippostad Day Capsules are available in:
 Aluminium (Alu/Alu) blister strips, sealed with aluminium foil
Blister strips are packed into cardboard cartons.
Pack sizes are 10, 12, 20 and 24 capsules.
Not all pack sizes are marketed.
Marketing Authorisation Holder
STADA Arzneimittel AG, Stadastrasse 2-18, D-61118 Bad Vilbel, Germany
This medicinal product is authorised in the Member States of the EEA under the
following names:
Germany
United Kingdom

PIL-common

Grippostad Tag Hartkapseln
Grippostad Day Capsules

7 of 8

UK/H/4922/001/II/005

2015-10-15

This leaflet was last revised in 09/2015.

PIL-common

8 of 8

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide