Vitamin B12 Side Effects
Generic name: cyanocobalamin
Medically reviewed by Drugs.com. Last updated on Oct 25, 2024.
Note: This document provides detailed information about Vitamin B12.
For healthcare professionals
Applies to cyanocobalamin: compounding powder, injectable solution, intramuscular solution, nasal gel, nasal spray, oral liquid, oral lozenge, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, sublingual liquid, sublingual lozenge, sublingual tablet Side Effects associated with cyanocobalamin. Some dosage forms listed on this page may not apply specifically to the brand name Vitamin B12.
For healthcare professionals
Applies to cyanocobalamin: compounding powder, injectable solution, intramuscular solution, nasal gel, nasal spray, oral liquid, oral lozenge, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, sublingual liquid, sublingual lozenge, sublingual tablet.
Cardiovascular adverse events
- Frequency not reported: Congestive heart failure, peripheral vascular thrombosis, cardiac arrest, low blood pressure[Ref]
Hypersensitivity
- Frequency not reported: Anaphylactic shock and death, allergic hypersensitivity reactions[Ref]
Patients sensitized to the injectable product are often able to tolerate the oral route without problems.[Ref]
Gastrointestinal
- Frequency not reported: Mild transient diarrhea, prolonged abdominal pain, prolonged nausea or vomiting[Ref]
Nervous system
- Frequency not reported: Severe dizziness, drowsiness, muscular paralysis, loss of consciousness[Ref]
Dermatologic
- Frequency not reported: Itching, transitory exanthema, acneiform eruptions, bullous eruptions[Ref]
Respiratory
- Frequency not reported: Pulmonary edema[Ref]
Metabolic
- Frequency not reported: Hypokalemia[Ref]
Oncologic
- Frequency not reported: Polycythemia vera[Ref]
Ocular
- Frequency not reported: Vision problems[Ref]
Other
- Frequency not reported: Feeling of swelling of entire body[Ref]
References
1. Cerner Multum, Inc. "Australian Product Information."
2. (2017) "Product Information. Cyanocobalamin (cyanocobalamin)." West Ward Pharmaceutical Corporation
3. Cerner Multum, Inc. "UK Summary of Product Characteristics."
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Further information
Vitamin B12 side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.