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Tham Side Effects

Generic name: tromethamine

Medically reviewed by Drugs.com. Last updated on Jun 14, 2022.

Note: This document contains side effect information about tromethamine. Some of the dosage forms listed on this page may not apply to the brand name Tham.

For the Consumer

Applies to tromethamine: intravenous solution

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
  • Signs of high potassium levels like a heartbeat that does not feel normal; feeling confused; feeling weak, lightheaded, or dizzy; feeling like passing out; numbness or tingling; or shortness of breath.
  • Trouble breathing, slow breathing, or shallow breathing.
  • Shortness of breath, a big weight gain, or swelling in the arms or legs.
  • Fever.
  • This drug may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to tromethamine: compounding powder, intravenous solution

Cardiovascular

Frequency not reported: Chemical phlebitis, venospasms[Ref]

Dermatologic

Frequency not reported: Extravasation tissue damage and sloughing[Ref]

Endocrine

Frequency not reported: Transient depression of blood glucose[Ref]

Hepatic

Frequency not reported: Hepatocellular necrosis[Ref]

Local

Frequency not reported: Infection at site of injection, venous thrombosis or phlebitis from site of injection extravasation[Ref]

Metabolic

Frequency not reported: Hypervolemia[Ref]

Other

Frequency not reported: Febrile response[Ref]

Respiratory

Frequency not reported: Ventilatory depression, respiratory depression[Ref]

References

1. "Product Information. Tham (tromethamine)." Abbott Pharmaceutical (2001):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.