Skip to main content

Poliovirus vaccine, inactivated Side Effects

Medically reviewed by Last updated on Nov 17, 2023.

Applies to poliovirus vaccine, inactivated: injection suspension.

Serious side effects

Along with its needed effects, poliovirus vaccine, inactivated may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking poliovirus vaccine, inactivated:

Symptoms of allergic reaction

More common

Other side effects

Some side effects of poliovirus vaccine, inactivated may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to poliovirus vaccine, inactivated: injectable suspension.


Very common (10% or more): Injection site pain (34%), local tenderness (29.4%), local swelling (11.4%)

Common (1% to 10%): Local erythema

Uncommon (0.1% to 1%): Injection site mass

Postmarketing reports: Injection site reaction (including injection site rash)[Ref]


Very common (10% or more): Temperature over 102F (38%)

Common (1% to 10%): Persistent crying

Frequency not reported: Death

Postmarketing reports: Pyrexia[Ref]


Very common (10% or more): Irritability (64.5%), tiredness (60.7%) fussiness, sleepiness

Postmarketing reports: Agitation[Ref]


Very common (10% or more): Anorexia (16.6%)[Ref]


Common (1% to 10%): Vomiting, diarrhea[Ref]

Nervous system

Frequency not reported: Guillain-Barre syndrome

Postmarketing reports: Convulsion, febrile convulsion, headache, paresthesia[Ref]


Postmarketing reports: Type I hypersensitivity reaction (including allergic reaction, anaphylactic reaction, and anaphylactic shock)[Ref]


Postmarketing reports: Arthralgia, myalgia[Ref]


Postmarketing reports: Lymphadenopathy[Ref]


Postmarketing reports: Rash, urticaria[Ref]


1. Product Information. Ipol (IPV) (poliovirus vaccine, inactivated). Aventis Pharmaceuticals. 2002.

2. Cerner Multum, Inc. Australian Product Information.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.