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Orange Medic Head Lice Treatment Side Effects

Generic name: permethrin topical

Medically reviewed by Last updated on Jun 28, 2024.

Note: This document contains side effect information about permethrin topical. Some dosage forms listed on this page may not apply to the brand name Orange Medic Head Lice Treatment.

Applies to permethrin topical: topical cream, topical liquid, topical lotion.

Serious side effects

Along with its needed effects, permethrin topical (the active ingredient contained in Orange Medic Head Lice Treatment) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Other side effects

Some side effects of permethrin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

For Healthcare Professionals

Applies to permethrin topical: topical cream, topical kit, topical lotion, topical solution, topical spray.


Local side effects have included mild and transient burning and stinging usually associated with the severity of infestation.[Ref]


Dermatological side effects have included pruritus (7%), erythema (1% to 2%), and rash (1% to 2%).[Ref]

Nervous system

Nervous system side effects have included numbness and tingling (1% to 2%). Headache and dizziness have also been reported. Rare occurrences of seizure have been reported; however, an association with the use of permethrin topical (the active ingredient contained in Orange Medic Head Lice Treatment) has not been confirmed.[Ref]


Gastrointestinal side effects have included abdominal pain, diarrhea, and nausea and/or vomiting.[Ref]


General side effects have included fever.[Ref]

Frequently asked questions

More about Orange Medic Head Lice Treatment (permethrin topical)

Patient resources

Other brands

Elimite, Nix, Nix Complete Lice Treatment System, Nix Lice Control, ... +4 more

Professional resources

Other brands

Elimite, Nix

Related treatment guides


1. (2006) "Product Information. Elimite (permethrin topical)." Allergan Inc

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.