Givinostat Side Effects
Medically reviewed by Drugs.com. Last updated on Dec 10, 2024.
Applies to givinostat: oral suspension.
Side effects include:
Most common adverse reactions (≥10%): diarrhea, abdominal pain, thrombocytopenia, nausea/vomiting, hypertriglyceridemia, pyrexia.
For healthcare professionals
Applies to givinostat: oral suspension.
General adverse events
The most common side effects were abdominal pain, diarrhea, hypertriglyceridemia, nausea or vomiting, pyrexia, and thrombocytopenia.[Ref]
Cardiovascular
- Frequency not reported: QTc prolongation
Dermatologic
- Common (1% to 10%): Rash
Endocrine
- Common (1% to 10%): Hypothyroidism, increased thyroid stimulating hormone
Gastrointestinal
- Very common (10% or more): Abdominal pain (34%), diarrhea (37%), nausea/vomiting (32%)
- Common (1% to 10%): Constipation
Hematologic
- Very common (10% or more): Thrombocytopenia (33%)
Thrombocytopenia included a decreased platelet count and thrombocytopenia.
Metabolic
- Very common (10% or more): Hypertriglyceridemia (23%)
- Common (1% to 10%): Decreased appetite
Musculoskeletal
- Common (1% to 10%): Arthralgia, myalgia
Other
- Very common (10% or more): Pyrexia (13%)
- Common (1% to 10%): Fatigue
References
1. (2024) "Product Information. Duvyzat (givinostat)." ITF Therapeutics, LLC
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Further information
Givinostat side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
