Gelfoam Plus Side Effects
Generic Name: thrombin topical
Note: This page contains information about the side effects of thrombin topical. Some of the dosage forms included on this document may not apply to the brand name Gelfoam Plus.
For the Consumer
Applies to thrombin topical: topical application powder for solution
In addition to its needed effects, some unwanted effects may be caused by thrombin topical (the active ingredient contained in Gelfoam Plus). In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking thrombin topical, check with your doctor or nurse immediately:More common:
- Difficulty breathing
- pain in the chest, groin, or legs, especially the calves
- severe, sudden headache
- slurred speech
- sudden loss of coordination
- sudden, severe weakness or numbness in the arm or leg
- sudden, unexplained shortness of breath
- vision changes
Minor Side Effects
Some of the side effects that can occur with thrombin topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Rare
- Burning feeling, redness, swelling, itching, or skin rash at the place of application
For Healthcare Professionals
Applies to thrombin topical: nasal powder for reconstitution, topical kit, topical pad, topical powder for reconstitution, topical solution
Hematologic side effects including increased activated partial thromboplastin time, increased international normalized ratio, decreased lymphocyte count, prolonged prothrombin time, and increased neutrophil count have been reported.[Ref]
Dermatologic side effects including pruritus have been reported.[Ref]
Gastrointestinal side effects including nausea and vomiting have been reported.
Local side effects including incision site complications have been reported.[Ref]
Immunologic side effects including antibody development have been reported.[Ref]
Hypersensitivity side effects including hypersensitivity reactions have been reported.[Ref]
1. "Product Information. Recothrom (thrombin topical)." ZymoGenetics Inc, Seattle, WA.
Not all side effects for Gelfoam Plus may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
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