Crenessity Side Effects

Generic name: crinecerfont

Medically reviewed by Drugs.com. Last updated on Apr 10, 2025.

Note: This document provides detailed information about Crenessity Side Effects associated with crinecerfont. Some dosage forms listed on this page may not apply specifically to the brand name Crenessity.

Applies to crinecerfont: oral capsule, oral solution.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• decreased adrenal gland hormones--nausea, vomiting, stomach pain, loss of appetite, feeling tired or light-headed, muscle or joint pain, skin discoloration, craving salty foods; or

• increased adrenal gland hormones--hunger, weight gain, swelling, skin discoloration, slow wound healing, sweating, acne, increased body hair, tiredness, mood changes, muscle weakness, missed menstrual periods, sexual changes.

Common side effects may include:

• tiredness, headache, dizziness;

• stuffy nose, nosebleeds;

• stomach pain, loss of appetite; or

• back pain, muscle or joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to crinecerfont: oral capsule, oral solution.

Gastrointestinal adverse events

• Very common (10% or more): Abdominal pain (up to 13%)
• Frequency not reported: dyspepsia, nausea, and vomiting^[Ref]

Hypersensitivity

• Frequency not reported: Throat tightness, angioedema, generalized rash^[Ref]

Immunologic

• Very common (10% or more): Decreased neutrophil count (up to 37%)^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia, arthralgia, back pain, myalgia^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 25%)
• Common (1% to 10%): Dizziness^[Ref]

Psychiatric

• Common (1% to 10%): Suicidal ideation
• Frequency not reported: Restlessness, apathy^[Ref]

Respiratory

• Common (1% to 10%): Nasal congestion, epistaxis^[Ref]

Metabolic

• Common (1% to 10%): Decreased appetite
• Frequency not reported: Acute adrenal insufficiency, adrenal crisis^[Ref]

Other

• Very common (10% or more): Fatigue (up to 25%)^[Ref]

See also:

Further information

Crenessity side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer