Conray Side Effects
Generic Name: iothalamate
Medically reviewed by Drugs.com. Last updated on Sep 6, 2020.
Note: This document contains side effect information about iothalamate. Some of the dosage forms listed on this page may not apply to the brand name Conray.
For the Consumer
Applies to iothalamate: injection solution, intravenous solution, urethral solution
- This drug must not be given into the spine.
- Very bad health problems, paralysis, and death have happened when contrast has been given into blood vessels in the spinal cord. Talk with the doctor.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Stuffy nose.
- Shortness of breath.
- Blue or gray skin color.
- Chest pain or pressure.
- Fast or abnormal heartbeat.
- Very bad dizziness or passing out.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Very bad skin reactions (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen from 1 hour to several weeks after getting this drug. These skin reactions can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
Injection (if given in an artery or vein):
- This drug may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
For all uses of this drug:
- Feeling of warmth.
- Sweating a lot.
- Upset stomach or throwing up.
For use in the bladder:
- Irritation where this drug is used.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to iothalamate: injectable solution
Uncommon (0.1% to 1%): Erythema, rash
Rare (less than 0.1%): Angioedema, diaphoresis
Frequency not reported: Ecchymosis and tissue necrosis[Ref]
Rare (0.01% to 0.1%): Diarrhea, dry mouth, tongue edema
Common (1% to 10%): Anaphylactoid reactions
Frequency not reported: Dermal manifestations (urticaria with or without pruritus, erythema, maculopapular rash); dry mouth, sweating, conjunctival symptoms; facial, peripheral, and angioneurotic edema; symptoms related to the respiratory system include sneezing, nasal stuffiness, coughing, choking, dyspnea, chest tightness and wheezing, which may be initial manifestations of more severe and infrequent reactions including asthmatic attack, laryngospasm and bronchospasm with or without edema, pulmonary edema, apnea and cyanosis[Ref]
Common (1% to 10%): Rhinitis
Uncommon (0.1% to 1%): Coughing, dyspnea
Rare (0.01% to 0.1%): Larynx edema
Very rare (less than 0.01%): Apnea, bronchospasm[Ref]
Uncommon (0.1% to 1%): Hypotension
Frequency not reported: Generalized vasodilation, flushing and venospasm; occasionally thrombosis; severe cardiovascular responses include rare cases of hypotensive shock, coronary insufficiency, cardiac arrhythmia, fibrillation and arrest; extravasation with burning pain; hematomas; vascular constriction due to injection rate; thrombosis[Ref]
These severe reactions are usually reversible with prompt and appropriate management; however, fatalities have occurred.[Ref]
Uncommon (0.1% to 1%): Thyroid function tests indicative of hypothyroidism or transient thyroid suppression in adults and pediatric patients (including infants)[Ref]
Uncommon (0.1% to 1%): Periorbital edema
Rare (0.01% to 0.1%): Conjunctivitis
Very rare (less than 0.01%): Vision disorders[Ref]
Rare (less than 0.1%): Injection side reaction[Ref]
Rare (0.01% to 0.1%): Dizziness; paraesthesia; taste perversion
Very rare (less than 0.01%): Agitation, coma, convulsions, dyskinesia, paralysis, tremor, somnolence
Frequency not reported: Aphasia; syncope, paresis; paralysis resulting from spinal cord injury and pathology associated with syndrome of transverse myelitis; visual field losses which are usually transient but may be permanent; coma and death; headache, trembling, shaking, numbness[Ref]
Very rare (less than 0.01%): Thirst[Ref]
Very rare (less than 0.01%): Involuntary muscle contractions, myalgia, leg pain
Frequency not reported: Spasm[Ref]
Very common (10% or more): Hot flushes, pain
Rare (0.01% to 0.1%): Malaise
Very rare (less than 0.01%): Edema, abnormal crying
Frequency not reported: Chills without fever and lightheadedness[Ref]
Very rare (less than 0.01%): Acute renal failure, decrease in renal function
Frequency not reported: Temporary renal shutdown or other nephropathy[Ref]
Frequency not reported: Red blood cell clumping and agglutination, crenation and interference in clot formation[Ref]
1. "Product Information. Conray (iothalamate)." Mallinckrodt Medical Inc, St. Louis, MO.
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
More about Conray (iothalamate)
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- Drug class: ionic iodinated contrast media
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.