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Cantharidin topical Side Effects

Medically reviewed by Last updated on Oct 17, 2023.

Applies to cantharidin topical: topical application solution.

Serious side effects of Cantharidin topical

Along with its needed effects, cantharidin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cantharidin topical:

More common

Incidence not known

For Healthcare Professionals

Applies to cantharidin topical: topical liquid.


Adverse reactions were primarily local skin reactions at the application site which was reported in 97% of patients and discontinuation due to adverse reactions was reported in 2.3% of patients.[Ref]


Common (1% to 10%): Moderate contact dermatitis[Ref]


Very common (10% or more): Mild application site dryness (19%), mild application site discoloration (28%), mild application site erythema (24%), mild application site scab (39%), mild application site pruritus (47%), mild application site pain (41%), mild application site vesicles (60%)

Common (1% to 10%): Mild application site erosion, mild application site edema[Ref]


1. "Product Information. Ycanth (cantharidin topical)." Verrica Pharmaceuticals Inc

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.