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Cantharidin Topical Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 17, 2025.

Applies to cantharidin topical: topical application solution.

Precautions

It is very important that your doctor check your progress closely to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

This medicine may cause eye problems if it gets into your eyes. Check with your doctor right away if you or your child has blurred vision or blue-green halos seen around objects, dry eyes, or sensitivity of the eyes to light.

Skin reactions may occur after treatment with this medicine. Check with your doctor right away if you have breakdown of the outer layer of skin, dry skin, lightening or darkening of the skin, or small fluid filled or non-fluid filled raised blisters on or around the treated areas. You may wash the treated area with soap and water 24 hours after application. Do not use a washcloth, abrasive material, or vigorous rubbing because it could be painful.

Serious side effects of cantharidin topical

Along with its needed effects, cantharidin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cantharidin topical:

More common side effects

  • changes in color of the skin
  • flushing, redness of the skin
  • skin ulcers
  • swelling of the skin
  • unusually warm skin

Incidence not known

  • blurred vision or blue-green halos seen around objects
  • dry eyes
  • sensitivity of the eyes to light

For healthcare professionals

Applies to cantharidin topical: topical liquid.

General adverse events

Adverse reactions were primarily local skin reactions at the application site which was reported in 97% of patients and discontinuation due to adverse reactions was reported in 2.3% of patients.[Ref]

Dermatologic

Local

See also:

References

1. "Product Information. Ycanth (cantharidin topical)." Verrica Pharmaceuticals Inc

Further information

Cantharidin topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.