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Vancomycin Pregnancy and Breastfeeding Warnings

Vancomycin is also known as: Firvanq, Lyphocin, Vancocin, Vancocin HCl, Vancocin HCl Pulvules

Vancomycin Pregnancy Warnings

This drug should be used during pregnancy only if clearly needed.

AU TGA pregnancy category: B2
US FDA pregnancy category:
-Oral capsules: B
-Parenteral formulations: C

Comments:
-If treatment is necessary, some experts recommend close monitoring of maternal blood to reduce the risk of ototoxicity and nephrotoxicity in the fetus.
-Pregnant patients may require higher doses to achieve therapeutic concentrations.

Animal models have failed to reveal evidence of fetal harm. There are no controlled data in human pregnancy.

AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.

US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Vancomycin Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Yes

Comments:
-Some experts recommend using this drug with caution during breastfeeding.
-The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. Cerner Multum, Inc. "Australian Product Information." O 0
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Vancocin (vancomycin)." Lilly, Eli and Company, Indianapolis, IN.

References for breastfeeding information

  1. Giles FJ, DeAngelo DJ, Baccarani M, et al. "Optimizing outcomes for patients with advanced disease in chronic myelogenous leukemia." Semin Oncol 35(1 Suppl 1) (2008): S1-17; quiz S18-20
  2. Cerner Multum, Inc. "Australian Product Information." O 0
  3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  4. "Product Information. Vancocin (vancomycin)." Lilly, Eli and Company, Indianapolis, IN.
  5. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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