Skip to Content

Sodium bicarbonate Pregnancy and Breastfeeding Warnings

Sodium bicarbonate is also known as: Bell/ans, Neut

Sodium bicarbonate Pregnancy Warnings

Due to the undesirable side effects of sodium loading--edema and weight gain--the use of alternative antacids has been advocated by some experts. In one unblinded, controlled study of the maternal and fetal effects of 150 mEq of sodium bicarbonate, use of the drug was associated with significantly elevated maternal arterial pH, pC02, and base excess and significantly elevated umbilical arterial pH, p02, and base excess at delivery. There were apparent adverse effects of the infusion on the mothers, and no mention of adverse effects on the fetuses or newborns.

Sodium bicarbonate has been assigned to pregnancy category C by the FDA. There are no animal or human reproductive data. Some experts consider the use of sodium bicarbonate as an antacid during human pregnancy to be relatively contraindicated because of the availability of preferable therapeutic agents. Sodium bicarbonate should only be given during pregnancy when benefit outweighs risk.

See references

Sodium bicarbonate Breastfeeding Warnings

There are no data on the excretion of sodium bicarbonate into human milk.

See references

References for pregnancy information

  1. Clark RB, Stephens SR, Greifenstein FE "Fetal and maternal effects of bicarbonate administration during labor." Anesth Analg 50 (1971): 713-8
  2. "Product Information. Sodium Bicarbonate (sodium bicarbonate)." Astra USA, Westborough, MA.
  3. Berkowitz R, Coustan D, Mochizuki T. "Handbook for Prescribing Medications During Pregnancy. 2nd ed." Boston, MA: Little, Brown, and Company (1986): 242

References for breastfeeding information

  1. "Product Information. Sodium Bicarbonate (sodium bicarbonate)." Astra USA, Westborough, MA.

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.