Skip to Content

Nafarelin Pregnancy and Breastfeeding Warnings

Nafarelin is also known as: Synarel

Nafarelin Pregnancy Warnings

Animal models have revealed evidence of dose-related increased fetal mortality and decreased fetal weight when given this drug intramuscularly. An animal model species revealed evidence of major fetal malformations when this drug was administered during organogenesis. There are no controlled data in human pregnancy. AU TGA pregnancy category D: Drugs which have caused, are suspected to have caused or may be expected to cause, an increased incidence of human fetal malformations or irreversible damage. These drugs may also have adverse pharmacological effects. Accompanying texts should be consulted for further details. US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Use in women who are or may become pregnant is contraindicated. AU TGA pregnancy category: D US FDA pregnancy category: X Comments: -Pregnancy should be excluded prior to starting treatment, and barrier methods of contraception should be used for the duration of treatment. -If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential harm to the fetus. Some experts recommend discontinuation of treatment if a patient becomes pregnant. The manufacturer product information should be consulted regarding recommendations.

See references

Nafarelin Breastfeeding Warnings

Use is contraindicated. Excreted into human milk: Unknown Excreted into animal milk: Unknown Comments: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Synarel (nafarelin)." Roche Laboratories, Nutley, NJ.
  2. Cerner Multum, Inc. "Australian Product Information." O 0
  3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  4. "Product Information. Synarel Nasel Solution (nafarelin nasal)." Searle, Chicago, IL.
  5. "Product Information. Synarel (nafarelin nasal)." Pfizer U.S. Pharmaceuticals Group, New York, NY.

References for breastfeeding information

  1. Cerner Multum, Inc. "Australian Product Information." O 0
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Synarel (nafarelin nasal)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
  4. "Product Information. Synarel (nafarelin)." Roche Laboratories, Nutley, NJ.
  5. "Product Information. Synarel Nasel Solution (nafarelin nasal)." Searle, Chicago, IL.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide