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Chenodeoxycholic acid Pregnancy and Breastfeeding Warnings

Chenodeoxycholic acid is also known as: Chenodal

Medically reviewed on Apr 16, 2017

Chenodeoxycholic acid Pregnancy Warnings

Animal studies have revealed evidence of hepatic, renal, and adrenal lesions at doses 1 to 2 times the maximum recommended human dose. There are no controlled data in human pregnancy.

US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Use is contraindicated in women who are or may become pregnant.
-Some experts recommend: Use is not recommended.

US FDA pregnancy category: X

Comments:
-Some experts recommend that use is not recommended in women of childbearing potential not using contraception.
-If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential harm to the fetus.
-Women of childbearing potential should be advised to avoid becoming pregnant while receiving this medication.
-Adequate methods of contraception should be encouraged; hormonal contraceptives are not recommended during treatment.

See references

Chenodeoxycholic acid Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
-Some experts recommend: Use is not recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comment: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Chenodal (chenodeoxycholic acid)." Manchester Pharmaceutical, Fort Collins, CO.
  2. EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."

References for breastfeeding information

  1. EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports. Available from: URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/includes/medicines/medicines_landingpage.jsp&mid."
  2. "Product Information. Chenodal (chenodeoxycholic acid)." Manchester Pharmaceutical, Fort Collins, CO.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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