Atovaquone Pregnancy and Breastfeeding Warnings
Medically reviewed by Drugs.com. Last updated on Feb 27, 2023.
Atovaquone is also known as: Mepron
Atovaquone Pregnancy Warnings
Atovaquone has been assigned to pregnancy category C. Animal studies have revealed evidence of increased resorption and fetal harm; it is unclear if these effects were due to direct embryotoxicity and fetotoxicity or secondary to maternal toxicity. There are no controlled data in human pregnancies. Atovaquone should only be given during pregnancy when benefit outweighs risk.
Atovaquone Breastfeeding Warnings
There are no data on the excretion of atovaquone into human milk. In a rat study, atovaquone milk concentration was 30% of maternal plasma concentration. The manufacturer recommends that caution be used when administering atovaquone to nursing women. The U.S. Public Health Service Centers for Disease Control and Prevention advise HIV-infected women not to breast-feed to avoid postnatal transmission of HIV to a child who may not yet be infected.
See also
References for pregnancy information
- "Product Information. Mepron (atovaquone)." Glaxo Wellcome (2002):
References for breastfeeding information
- "Product Information. Mepron (atovaquone)." Glaxo Wellcome (2002):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
