Weighted Vests Do Not Prevent Weight Loss-Linked Bone Loss at Hip
TUESDAY, July 1, 2025 -- For older adults with obesity, neither weighted vest use nor resistance training (RT) mitigates weight loss (WL)-associated bone loss at the hip, according to a study published online June 20 in JAMA Network Open.
Kristen M. Beavers, Ph.D., from the Wake Forest University School of Medicine in Winston-Salem, North Carolina, and colleagues examined the effect of 12 months of weighted vest use during WL on indicators of bone health compared with WL alone and WL plus progressive RT in a single-blind, randomized clinical trial of older adults living with obesity.
The researchers randomly assigned 150 older adults with obesity to one of three groups (50 to WL [caloric restriction targeting 10 percent WL, with adequate calcium, vitamin D, and protein], 50 to WL plus weighted vest for eight hours/day [WL + VEST], and 50 to WL + RT [three sessions per week]); 133 participants completed the trial. All groups achieved similar, significant WL, ranging from 9.0 to 11.2 percent. All treatment groups had a significant decrease in total hip trabecular volumetric bone mineral density at 12 months, ranging from −1.2 to −1.9 percent, with no difference between the WL+VEST and WL groups and noninferiority of WL+VEST versus WL+RT. For total hip areal bone mineral density, similar effects were observed.
"We hoped that replacing lost weight externally or increasing mechanical loading through exercise would preserve bone, but our findings show that these strategies alone may not be enough," Beavers said in a statement.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Read this next
Metabolic Surgery Has Greater Long-Term Benefits Than GLP-1 Receptor Agonists
WEDNESDAY, Oct. 1, 2025 -- People with obesity and type 2 diabetes who undergo metabolic surgery live longer and face fewer serious health problems compared with patients treated...
Patients With Extreme Obesity Face Limitations to Accessing Specialty Care
TUESDAY, Sept. 30, 2025 -- Patients weighing more than 450 lb face considerable limitations when attempting to access specialty care, according to a research letter published...
GLP-1 Receptor Agonists Tied to Reduced Mortality in Patients With Psoriasis
TUESDAY, Sept. 30, 2025 -- Patients with psoriasis treated with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have better long-term outcomes compared with those taking...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.