Vaping Tied to Increased Risk for Smoking, Other Harms in Young People
By Lori Solomon HealthDay Reporter
Medically reviewed by Drugs.com
FRIDAY, Aug. 22, 2025 -- There are consistent associations between vaping and negative outcomes in young people, including subsequent smoking, substance use, and poor physical and mental health, according to a review published online Aug. 19 in Tobacco Control.
Su Golder, Ph.D., from the University of York in the United Kingdom, and colleagues conducted a systematic literature review to evaluate potential harms from electronic cigarettes in young people.
Based on 56 included reviews, the researchers observed a consistent, significant association between vaping and smoking initiation, supporting a causal relationship (pooled odds ratios [ORs] of 1.50 to 26.01; 21 systematic reviews), most of which suggested that young people using e-cigarettes are about three times more likely than those not using them to initiate smoking. Five systematic reviews showed a substantial association between e-cigarettes and substance use, including marijuana (pooled ORs, 2.72 to 6.04), alcohol (pooled ORs, 4.50 to 6.67), and binge drinking (pooled ORs, 4.51 to 6.73). The most common respiratory outcome was asthma, with consistent associations observed (diagnosis: ORs, 1.20 to 1.36; exacerbation: OR, 1.44). There were associations seen between vaping and suicidal outcomes in three systematic reviews, while six noted associations with injuries, predominantly explosion incidents. Other harmful outcomes included pneumonia, bronchitis, lower total sperm counts, dizziness, headaches, migraines, and oral health harms, although this evidence was largely derived from limited surveys or case series/reports.
“The consistency in the evidence is striking," Golder said in a statement. "Across multiple studies, young people who use e-cigarettes are more likely to smoke in the future. These findings support stronger public health measures to protect teens from the risks associated with vaping.”
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted August 2025
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.