Skip to main content

High Ultraprocessed Food Intake Linked to Active Psoriasis

Medically reviewed by Carmen Pope, BPharm. Last updated on Dec 4, 2024.

By Elana Gotkine HealthDay Reporter

TUESDAY, Dec. 3, 2024 -- High ultraprocessed food (UPF) intake is associated with active psoriasis, according to a research letter published online Nov. 27 in JAMA Dermatology.

Laetitia Penso, Ph.D., from Paris-Est University, and colleagues performed a cross-sectional study using data from the Nutri-Net-Santé cohort study to examine the association between UPF intake and active psoriasis. Participants were classified by their psoriasis status (never-had; nonactive; active) using a validated self-diagnosis questionnaire. UPF intake in grams/day was extracted and divided into tertiles, from minimum to maximum intake (tertiles 1 and 3, respectively).

Data were included for 18,528 participants, of whom 1,825 (10 percent) had psoriasis, with 803 active cases (4 percent). Compared with the never-had and nonactive groups, the active-psoriasis group had a lower proportion of females and a higher proportion of individuals with a body mass index (BMI) greater than 30 kg/m2. High-intensity physical activity occurred less often in the active and nonactive groups than the never-had group. The researchers found that UPF intake differed between the active and never-had groups in an unadjusted analysis (tertile 3 odds ratio, 1.52). High UPF intake was more likely than lower UPF intake in the active group after adjustments (tertile 3 adjusted odds ratio, 1.36).

"After adjustments for age, BMI, alcohol intake, and comorbidities, the results remained significant, suggesting that UPF intake has a proinflammatory action separate from high BMI," the authors write.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Posted December 2024

Read this next

Central Adiposity Measures Associated With Psoriasis Risk

TUESDAY, June 3, 2025 -- Central adiposity measures are strongly associated with psoriasis risk, with a stronger association in women, according to a research letter published...

Psoriasis Tied to Increased Risk for Sleep Disorders

MONDAY, June 2, 2025 -- Both mild and moderate-to-severe psoriasis are significantly associated with an increased risk for sleep disorders, according to a study published online...

Residual Inflammation Seen in One-Third of Patients With Psoriasis on Biologics

WEDNESDAY, May 21, 2025 -- For patients with psoriasis receiving biologic therapy, residual inflammation (RI), defined as increased inflammatory markers in blood, characterized by...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.