Study Reveals No Link Between HDL Cholesterol and Movement Disorders
By Lori Solomon HealthDay Reporter
FRIDAY, Sept. 20, 2024 – There is no correlation between high-density lipoprotein cholesterol (HDL-C) levels and a patient's risk for developing movement disorders while taking an antipsychotic, according to a study published in the April-June issue of Innovations in Clinical Neuroscience.
Carolyn O’Donnell, Pharm.D., from the Edward Hines Jr. Veterans Administration Hospital in Hines, Illinois, and colleagues investigated associations between patients taking antipsychotics with low HDL-C and the risk for developing a movement disorder. The analysis included 89 adult patients at an inpatient state psychiatric facility.
The researchers report that only eight patients had an Abnormal Involuntary Movement Scale score greater than 0 and HDL-C levels ranged from 17 mg/dL to 83 mg/dL. There was no statistically significant association seen when comparing a patient's movement disorder, Abnormal Involuntary Movement Scale scores, and HDL-C levels.
"It is our hope that our research will support prioritized prescribing decisions focused more directly on removing offending medications, versus exploring hypothesized physiologic factors such as HDL-C, because earlier recognition of drug-induced movement disorders permits rapid intervention and decreased risk of permanently disfiguring and debilitating extrapyramidal symptoms," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted September 2024
Read this next
Adverse Childhood Experiences Tied to Endometriosis Risk
FRIDAY, June 13, 2025 -- Early life adversity is associated with an increased risk of being diagnosed with endometriosis later in life, according to a study published online June...
Systemic Social Factors May Increase the Risk of Psychotic Experiences
TUESDAY, June 10, 2025 -- Experiences with discrimination may increase the risk of psychotic experiences among marginalized young adults, according to a study published online May...
Better Adherence to Antipsychotics Linked to Lower Vehicle Crash Risk
MONDAY, June 9, 2025 -- For drivers with schizophrenia, better adherence to antipsychotic medications is associated with lower motor vehicle crash risk, according to a study...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.