Study Looks at Impact of Peritoneal Dialysis on Thyroid Function
By Elana Gotkine HealthDay Reporter
MONDAY, Sept. 23, 2024 -- Patients undergoing peritoneal dialysis (PD) have significantly higher thyroxine (T4) concentrations than hemodialysis (HD) patients and higher free T4 (FT4) concentrations at 12 and 24 months, according to a study published online Sept. 7 in Seminars in Dialysis.
Jelić Pranjić Ita, M.D., from the University Hospital Center Rijeka in Croatia, and colleagues conducted a prospective single-center study to examine thyroid function in 18 PD patients during a 24-month period. Data were compared to those from concurrently treated HD patients.
The researchers found that some of the PD patients had elevated thyroid-stimulating hormone levels initially, which normalized during follow-up, despite longer duration of dialysis. PD patients had significantly higher T4 concentrations at baseline and higher FT4 concentrations at 12 and 24 months compared with HD patients. At baseline and at 12 and 24 months, free triiodothyronine (FT3) levels were significantly higher; after the beginning of the study, T3 levels were within the reference interval. In PD patients, there was a positive association between T4 levels and 24-hour diuresis after 12 months.
"PD's continuous nature offers the benefit of better preservation of residual kidney function and gradual toxin removal," the authors write. "However, the complete precise factors influencing potential differences in survival have not been fully elucidated."
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted September 2024
Read this next
Racialized Economic Segregation Linked to Advanced Cancer Diagnosis
FRIDAY, Aug. 1, 2025 -- People living in racially and economically segregated neighborhoods are more likely to be diagnosed with advanced-stage breast and cervical cancer...
New Subtype of Diabetes Identified in Sub-Saharan Africans, Black Americans
FRIDAY, Aug. 1, 2025 -- A new diabetes subtype has been identified in Sub-Saharan Africans and Black Americans, according to a study published online July 21 in The Lancet...
Changes in Missouri Law Linked to Increased Breast Cancer Screening Rates
THURSDAY, July 31, 2025 -- Changes in Missouri law expanding breast cancer screening coverage have led to increased screening rates among Medicaid patients and an increased...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.