Study IDs Specific Anaphylactic Triggers Linked to Symptoms, Treatment
By Elana Gotkine HealthDay Reporter
THURSDAY, Dec. 26, 2024 -- Specific anaphylactic triggers are associated with symptoms and treatments, according to a study published online Nov. 15 in the International Archives of Allergy and Immunology.
Roy Khalaf, from McGill University in Montreal, and colleagues examined sociodemographic characteristics, clinical symptoms, and management of anaphylaxis among adults in a cross-sectional study. Data were included for 1,135 adults presenting to emergency departments with drug-induced anaphylaxis (DIA), venom-induced anaphylaxis, peanut-induced anaphylaxis, shellfish-induced anaphylaxis, tree-nut induced anaphylaxis (TIA), and nut-induced anaphylaxis (NIA) from April 2011 to November 2023.
The researchers found that 50.3 percent of the patients presented with food-induced anaphylaxis. Hypotension was more likely associated with DIA in terms of symptomatology (adjusted odds ratio, 1.20). Alcohol was more likely associated with NIA when adjusted for age at reaction and male sex (adjusted odds ratio, 1.51). In terms of management, TIA was more likely associated with inpatient epinephrine (adjusted odds ratio, 2.05), while DIA and TIA were less and more likely associated with outpatient antihistamine, respectively (adjusted odds ratios, 0.68 and 1.81, respectively).
"While our findings highlight associations between specific anaphylaxis triggers and symptom presentation, these associations do not imply a universal early warning system for diagnosing anaphylaxis," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted December 2024
Read this next
Cashew Identified as Increasingly Relevant Allergen Triggering Anaphylaxis in Children
WEDNESDAY, July 9, 2025 -- Cashew is an increasingly relevant allergen leading to anaphylaxis in children, according to a study published online June 13 in Allergy. Veronika...
Two-Hour Observation Probably Safe for Most Children With Anaphylaxis
THURSDAY, June 26, 2025 -- For most children who present to an emergency department with an acute allergic reaction requiring epinephrine, a two-hour observation period is...
Parents Delaying Introduction of Nuts and Eggs, Tied to Increase in Food Allergy Risk
WEDNESDAY, June 11, 2025 -- Most highly allergenic foods are introduced to infants at 6 to 9 months, but introduction of eggs and nuts is delayed beyond age 1 year in a large...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.