Standard-Criteria Kidney Transplant Offers Clear Survival Benefit Over Continued Dialysis
By Elana Gotkine HealthDay Reporter
TUESDAY, June 10, 2025 -- Transplantation with standard-criteria kidney offers a clear survival benefit, but this decreases with age and for those with a history of cardiovascular disease (CVD), according to a study presented at the annual congress of the European Renal Association, held from June 4 to 7 in Vienna.
Rachel Hellemans, M.D., Ph.D., from Antwerp University Hospital in Belgium, and colleagues examined the survival benefit of deceased donor kidney transplantation compared with continued dialysis in waitlisted patients with kidney failure. Data were included for 64,013 patients aged ≥20 years from the European Renal Association Registry database who were on dialysis while waitlisted for a first deceased donor kidney-only transplant.
Overall, 40,441 patients received a kidney transplant, either from a standard criteria donor (SCD)/donation after brain death (DBD), SCD/donation after circulatory death (DCD), expanded criteria donor (ECD)/DBD, or ECD/DCD (45.0, 12.1, 35.2, and 7.7 percent, respectively). The researchers found that higher five-year survival was seen in SCD transplant recipients versus dialysis patients. There was a decrease in survival benefits seen with age in ECD kidney transplant recipients, especially in recipients of DCD kidneys and recipients with CVD comorbidity: five-year survival was 57 and 58 percent for a 75-year-old ECD/DCD recipient or a 75-year-old ECD recipient with CVD, respectively, compared with 54 percent among patients continuing dialysis. In the oldest patients, early posttransplant mortality contributed to the reduced benefit.
"We found that transplantation with standard-criteria kidneys still offers a clear survival benefit at virtually every age, but in the oldest, most comorbid recipients receiving lower-quality organs, that edge can all but disappear," Hellemans said in a statement.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted June 2025
Read this next
Opportunistic Community Screening IDs Uncontrolled Cardiovascular Risk Factors
FRIDAY, Aug. 15, 2025 -- Opportunistic pop-up community screening identifies a high prevalence of uncontrolled cardiovascular risk factors, according to a study published online...
Risk for Incident CVD Increased for Women Who Reported Experiencing Stalking
MONDAY, Aug. 11, 2025 -- Women who report experiencing stalking and obtaining a restraining order have an increased risk for developing cardiovascular disease (CVD), according to...
Use of HEPA Filters Tied to Reduced Systolic BP
FRIDAY, Aug. 8, 2025 -- The use of in-home high-efficiency particulate arrestance (HEPA) filters is associated with reductions in systolic blood pressure (SBP) among individuals...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.